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How to get fromSan Diego to Lexingtonby plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

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There are 8 ways to get from San Diego to Lexington by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Columbia

    best
    1. Fly from San Diego International Airport (SAN) to Columbia (CAE)plane plane SAN - CAE
    6h 47m
    $423–1,586

  2. Fly to Greenville–Spartanburg International Airport, drive

    cheapest
    1. Fly from San Diego International Airport (SAN) to Greenville–Spartanburg International Airport (GSP)plane plane SAN - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Lexingtoncar car
    7h 59m
    $242–916

  3. Bus

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Camdenbus bus
    5. Take the bus from Camden to Columbia, SCbus bus Nyc
    2d 16h
    $482–904

  4. Train, bus via New Orleans

    1. Take the train from San Diego to Los Angelestrain train
    2. Take the train from Los Angeles to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Charlotte Amtrak Stationtrain train
    4. Take the bus from Charlotte Bus Station to Camdenbus bus
    5. Take the bus from Camden to Columbia, SCbus bus Nyc
    3d 2h
    $960–2,150

  5. Drive 2,339.4 mi

    1. Drive from San Diego to Lexingtoncar car 2,339.4 mi
    36h 29m
    $427–617

  6. Fly to Augusta Regional Airport At Bush Field, bus

    1. Fly from San Diego International Airport (SAN) to Augusta Regional Airport At Bush Field (AGS)plane plane SAN - AGS
    2. Take the bus from Augusta to Columbia, SCbus bus
    9h 59m
    $242–724

  7. Bus via Ciudad Juárez

    1. Take the bus from Cross Border Express, San Diego to El Pasobus bus Cbx
    2. Take the bus from El Paso Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Camdenbus bus
    5. Take the bus from Camden to Columbia, SCbus bus Nyc
    2d 20h
    $445–787

  8. Train, bus

    1. Take the train from San Diego to Fullerton Amtrak Stationtrain train
    2. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    4. Take the bus from S Saunders St at Chapanoke Rd - Raleigh to Columbia, SCbus bus
    3d 5h
    $1,145–2,419

San Diego International Airport (SAN) to Columbia (CAE) flights

Calendar107Weekly Planes
Duration8h 7mAverage Duration
Ticket$394Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Lexington.ExpandLaunch map view
  • Distance: 2,081.6 mi
  • Duration: 6h 47m

What companies run services between San Diego, CA, USA and Lexington, SC, USA?

Delta, American Airlines, and United Airlines fly from San Diego International Airport (SAN) to Columbia (CAE) hourly. Alternatively, you can take a bus from San Diego to Lexington via Los Angeles Union Station, St Louis Bus Station, Atlanta Bus Station, Camden, and Columbia, SC in around 2d 16h.

Airlines
Train operators
Bus operators

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