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How to get fromSan Diego to Louisvilleby plane, bus (Flixbus, Greyhound), bus, train, or car

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There are 8 ways to get from San Diego to Louisville by plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louisville International Airport

    best
    1. Fly from San Diego International Airport (SAN) to Louisville International Airport (SDF)plane plane SAN - SDF
    6h 56m
    $202–817

  2. Fly to Nashville, bus

    cheapest
    1. Fly from San Diego International Airport (SAN) to Nashville (BNA)plane plane SAN - BNA
    2. Take the bus from Nashville to Louisville, KYbus bus
    9h 13m
    $182–661

  3. Bus

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Louisville, KYbus bus
    2d 4h
    $361–690

  4. Bus, train (Amtrak)

    1. Take the bus from San Diego to Fullerton Amtrak Stationbus bus
    2. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Union Station to Louisville, KYbus bus
    2d 6h
    $785–1,609

  5. Drive 2,055.5 mi

    1. Drive from San Diego to Louisvillecar car 2,055.5 mi
    33h 22m
    $376–542

  6. Fly to Covington, bus

    1. Fly from San Diego International Airport (SAN) to Covington (CVG)plane plane SAN - CVG
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    8h 22m
    $227–782

  7. Fly to Indianapolis, bus

    1. Fly from San Diego International Airport (SAN) to Indianapolis (IND)plane plane SAN - IND
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    8h 45m
    $234–693

  8. Train, bus

    1. Take the train from San Diego to Los Angelestrain train
    2. Take the train from Los Angeles to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Louisville, KYbus bus
    2d 19h
    $851–1,788

San Diego to Louisville by bus

Calendar7Weekly Buses
Duration2d 4hAverage Duration
Ticket$361Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Louisville.ExpandLaunch map view
  • Distance: 1,806.9 mi
  • Duration: 6h 56m

What companies run services between San Diego, CA, USA and Louisville, KY, USA?

Southwest Airlines, American Airlines, and United Airlines fly from San Diego International Airport (SAN) to Louisville International Airport (SDF) every 4 hours. Alternatively, you can take a bus from San Diego to Louisville, KY via Los Angeles Union Station, St Louis Bus Station, and Evansville, IN in around 2d 4h.

Airlines
Train operators
Bus operators

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