There are 6 ways to get from San Diego to Mesquite, NV by plane, shuttle, train, bus, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, shuttle
best- Fly from San Diego International Airport (SAN) to Harry Reid International Airport (LAS)plane SAN - LAS
- Take a shuttle bus from Harry Reid International to Mesquite, NV - Eureka Casino
3h 42m$122–574Drive 410.3 mi
cheapest- Drive from San Diego to Mesquite, NVcar 410.3 mi
6h 41m$75–109Train, bus
- Take the train from San Diego to Los Angelestrain
- Take the bus from East Los Angeles to Las Vegasbus
- Take the bus from Las Vegas to Mesquite, NVbus
11h 18m$133–227Bus, shuttle
- Take the bus from Broadway & 1st Av to Escondido Transit Centerbus 235 / ...
- Take a shuttle bus from Escondido, CA - 796 W Valley PKWY to 1100 S Main St. - Las VegasCbx
- Take the bus from Harry Reid International to Mesquite, NVbus
12h 20m$82–143Bus via San Ysidro, CA
- Take the bus from San Ysidro, CA to Las Vegasbus San Ysidro
- Take the bus from Las Vegas to Mesquite, NVbus Las Vegas
11h 35m$112–169Bus
- Take the bus from San Diego to Las Vegas Stripbus FlixBus 2037
- Take the bus from Harry Reid International to Mesquite, NVbus Las Vegas
13h 56m$88–184
San Diego to Mesquite, NV by train, bus, and tram
Questions & Answers
The cheapest way to get from San Diego to Mesquite, NV is to drive which costs $75 - $110 and takes 6h 41m.
The fastest way to get from San Diego to Mesquite, NV is to fly and shuttle which takes 3h 42m and costs $120 - $600.
No, there is no direct bus from San Diego to Mesquite, NV. However, there are services departing from San Diego and arriving at Mesquite, NV via San Ysidro, CA and Las Vegas. The journey, including transfers, takes approximately 11h 35m.
The distance between San Diego and Mesquite, NV is 350 miles. The road distance is 412.7 miles.
The best way to get from San Diego to Mesquite, NV without a car is to train and bus which takes 11h 18m and costs $130 - $230.
It takes approximately 3h 42m to get from San Diego to Mesquite, NV, including transfers.
San Diego to Mesquite, NV bus services, operated by Tufesa, depart from San Ysidro, CA station.
San Diego to Mesquite, NV bus services, operated by Tufesa, arrive at Las Vegas station.
Yes, the driving distance between San Diego to Mesquite, NV is 413 miles. It takes approximately 6h 41m to drive from San Diego to Mesquite, NV.
There are 45+ hotels available in Mesquite, NV.
What companies run services between San Diego, CA, USA and Mesquite, NV, USA?
You can take a bus from San Diego to Mesquite, NV via San Ysidro Bus Terminal, San Ysidro, CA, and Las Vegas in around 11h 35m.
- Website
- southwest.com
Flights from San Diego International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $40–270
- Website
- alaskaair.com
Flights from San Diego International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $95–300
- Website
- flyfrontier.com
Flights from San Diego International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $80–260
- Website
- delta.com
Flights from San Diego International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $40–270
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Diego to Los Angeles
- Ave. Duration
- 2h 56m
- Frequency
- Hourly
- Estimated price
- $40–85
- Website
- Amtrak
- Phone
- +1 800-933-8320
- [email protected]
- Website
- St. George Shuttle
Shuttle from Harry Reid International to Mesquite, NV - Eureka Casino
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $30–45
- Website
- St. George Shuttle
- Phone
- +1 833 766 3553
- Website
- Tufesa
Bus from East Los Angeles to Las Vegas
- Ave. Duration
- 4h 45m
- Frequency
- Once daily
- Estimated price
- $60–85
- Schedules at
- Tufesa
- Adult One way
- $60–85
Bus from Las Vegas to Mesquite, NV
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $30–55
- Schedules at
- Tufesa
- Adult One way
- $30–55
Bus from San Ysidro, CA to Las Vegas
- Ave. Duration
- 8h
- Frequency
- Twice daily
- Estimated price
- $80–110
- Schedules at
- Tufesa
- Adult One way
- $80–110
Bus from Las Vegas to Mesquite, NV
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $30–55
- Schedules at
- Tufesa
- Adult One way
- $30–55
- Phone
- +1 619-557-4555
- Website
- MTS
Bus from Broadway & 1st Av to Escondido Transit Center
- Ave. Duration
- 1h 15m
- Frequency
- Every 20 minutes
- Estimated price
- $2–5
- Website
- MTS
- Schedules at
- MTS Schedules
- One Way - Adult/Youth
- $2–5
- [email protected]
- Website
- CBX Cross Border Express
Shuttle from Escondido, CA - 796 W Valley PKWY to 1100 S Main St. - Las Vegas
- Ave. Duration
- 6h 45m
- Frequency
- Once daily
- Estimated price
- $50–75
- Schedules at
- CBX Cross Border Express
- Phone
- +1 208-656-8824
- [email protected]
- Website
- Salt Lake Express
Bus from Harry Reid International to Mesquite, NV
- Ave. Duration
- 1h 26m
- Frequency
- Every 3 hours
- Estimated price
- $22–55
- Website
- Salt Lake Express
Bus from Harry Reid International to Mesquite, NV
- Ave. Duration
- 1h 26m
- Frequency
- Every 3 hours
- Estimated price
- $22–55
- Website
- Salt Lake Express
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from San Diego to Las Vegas Strip
- Ave. Duration
- 8h 40m
- Frequency
- Twice daily
- Estimated price
- $60–110
- Schedules at
- Flixbus USA
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