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How to get fromSan Diego to Missouriby plane, train (Amtrak), bus, car, or bus (Flixbus, Greyhound)

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There are 7 ways to get from San Diego to Missouri by plane, train (Amtrak), bus, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Lambert–St. Louis International Airport

    best
    1. Fly from San Diego International Airport (SAN) to Lambert–St. Louis International Airport (STL)plane plane SAN - STL
    4h 23m
    $140–189

  2. Fly to Springfield-Branson National Airport

    cheapest
    1. Fly from San Diego International Airport (SAN) to Springfield-Branson National Airport (SGF)plane plane SAN - SGF
    5h 48m
    $133–515

  3. Train (Amtrak)

    1. Take the train from San Diego to Fullerton Amtrak Stationtrain train Pacific Surfliner
    2. Take the train from Fullerton Amtrak Station to Kansas Citytrain train Southwest Chief
    38h 2m
    $583–1,267

  4. Bus via Ciudad Juárez

    1. Take the bus from Broadway & 5th Av to Escondido Transit Centerbus bus 235 / ...
    2. Take the bus from Escondido to San Bernardinobus bus
    3. Take the bus from San Bernardino to El Pasobus bus La
    4. Take the bus from El Paso to 2745 Southwest Blvd - Kansas Citybus bus
    38h 7m

  5. Drive 1,543 mi

    1. Drive from San Diego to Kansas Citycar car 1,543 mi
    27h 5m
    $282–407

  6. Fly to Kansas City

    1. Fly from San Diego International Airport (SAN) to Kansas City (MCI)plane plane SAN - MCI
    4h 45m
    $179–764

  7. Bus

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Tulsa Bus Stationbus bus
    3. Take the bus from Tulsa to Kansas Citybus bus
    43h 10m
    $321–585

San Diego to Missouri by train and tram (Amtrak)

Calendar7Weekly Services
Duration38h 2mAverage Duration
Ticket$583Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Missouri.ExpandLaunch map view
  • Distance: 1,568.7 mi
  • Duration: 4h 23m

What companies run services between San Diego, CA, USA and Missouri, USA?

Southwest Airlines, United Airlines, and American Airlines fly from San Diego International Airport (SAN) to Lambert–St. Louis International Airport (STL) 5 times a day. Alternatively, you can take a train from San Diego to Metro Center via Fullerton Amtrak Station, Kansas City, and Union Station in around 38h 2m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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