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How to get fromSan Diego to Palo Altoby plane, bus (Greyhound), train (Amtrak), car, train, or bus

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There are 6 ways to get from San Diego to Palo Alto by plane, bus (Greyhound), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Norman Y. Mineta San José International Airport

    best
    1. Fly from San Diego International Airport (SAN) to Norman Y. Mineta San José International Airport (SJC)plane plane SAN - SJC
    2h 21m
    $81–511

  2. Fly to San Francisco International Airport, Caltrain

    cheapest
    1. Fly from San Diego International Airport (SAN) to San Francisco International Airport (SFO)plane plane SAN - SFO
    2. Take the train from Millbrae Caltrain Southbound to California Avenue Caltrain Southboundtrain train
    2h 29m
    $74–244

  3. Bus (Greyhound)

    1. Take the bus from San Diego Greyhound Bus Stop to San Jose Diridon Stationbus bus Greyhound US0831
    11h 38m
    $75–139

  4. Train (Amtrak)

    1. Take the train from San Diego to Los Angelestrain train Pacific Surfliner
    2. Take the train from Los Angeles to San Josetrain train Coast Starlight
    14h 32m
    $175–370

  5. Drive 475.7 mi

    1. Drive from San Diego to Palo Altocar car 475.7 mi
    8h 4m
    $87–126

  6. Bus via San Ysidro

    1. Take the bus from San Ysidro to San Jose - King Rdbus bus San Ysidro
    14h
    $94–140

San Diego to Palo Alto by tram, bus, and train (Greyhound)

Calendar14Weekly Services
Duration11h 38mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Palo Alto.ExpandLaunch map view
  • Distance: 434.6 mi
  • Duration: 2h 21m

What companies run services between San Diego, CA, USA and Palo Alto, CA, USA?

Alaska Airlines, Inc. and Southwest Airlines fly from San Diego International Airport (SAN) to Norman Y. Mineta San José International Airport (SJC) hourly. Alternatively, Greyhound USA operates a bus from San Diego Greyhound Bus Stop to San Jose Diridon Station twice daily. Tickets cost $70–140 and the journey takes 9h 50m.

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Need to know: Greyhound

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