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How to get fromSan Diego to Port Saint Lucieby plane, bus, bus (Greyhound, Flixbus), train, car, or bus (Greyhound)

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There are 9 ways to get from San Diego to Port Saint Lucie by plane, bus, bus (Greyhound, Flixbus), train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Fort Lauderdale–Hollywood International Airport, bus

    best
    1. Fly from San Diego International Airport (SAN) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane SAN - FLL
    2. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus bus
    8h 27m
    $326–1,212

  2. Fly to Miami International Airport, bus

    cheapest
    1. Fly from San Diego International Airport (SAN) to Miami International Airport (MIA)plane plane SAN - MIA
    2. Take the bus from Sheridan Tri-Rail Station to Fort Piercebus bus
    9h 6m
    $182–517

  3. Bus

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Port St Luciebus bus
    2d 17h
    $439–839

  4. Train, bus

    1. Take the train from San Diego to Fullerton Amtrak Stationtrain train
    2. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Kissimmee Amtrak Stationtrain train
    4. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    3d 17h
    $1,214–2,809

  5. Drive 2,535.1 mi

    1. Drive from San Diego to Port Saint Luciecar car 2,535.1 mi
    39h 53m
    $463–669

  6. Fly to Orlando, bus

    1. Fly from San Diego International Airport (SAN) to Orlando (MCO)plane plane SAN - MCO
    2. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    9h 34m
    $259–960

  7. Fly to President Donald J. Trump International Airport, bus

    1. Fly from San Diego International Airport (SAN) to President Donald J. Trump International Airport (PBI)plane plane SAN - PBI
    2. Take the bus from West Palm Beach Bus Station to Port St Luciebus bus
    11h 22m
    $197–743

  8. Fly to Tampa, train, bus

    1. Fly from San Diego International Airport (SAN) to Tampa (TPA)plane plane SAN - TPA
    2. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    12h
    $227–749

  9. Bus via Ciudad Juárez

    1. Take the bus from Cross Border Express, San Diego to El Pasobus bus Cbx
    2. Take the bus from El Paso Bus Station to Houston Bus Stationbus bus
    3. Take the bus from Houston - Harrisburg Blvd to Ocalabus bus
    4. Take the bus from Ocala, FL to Kissimmee -1471 East Osceola Parkwaybus bus
    5. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    2d 18h
    $476–737

San Diego to Port Saint Lucie by bus

Calendar14Weekly Buses
Duration2d 17hAverage Duration
Ticket$439Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Port Saint Lucie.ExpandLaunch map view
  • Distance: 2,363 mi
  • Duration: 8h 27m

What companies run services between San Diego, CA, USA and Port Saint Lucie, FL, USA?

You can take a bus from San Diego to SW PSL Blvd & SE Bayshore Blvd via Los Angeles Union Station, Dallas Bus Station, Atlanta Bus Station, and SW Gatlin Blvd & SW Brescia St in around 2d 17h.

Airlines
Train operators
Bus operators

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