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How to get fromSan Diego to San Luis Obispoby plane, bus (Greyhound, Flixbus), train (Amtrak), or car

Find Transport to San Luis Obispo

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There are 4 ways to get from San Diego to San Luis Obispo by plane, bus (Greyhound, Flixbus), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from San Diego International Airport (SAN) to San Luis Obispo County Regional Airport (SBP)plane plane SAN - SBP
    2h 24m
    $171–344
  2. Bus

    cheapest
    1. Take the bus from San Diego to Los Angeles Union Stationbus bus Tijuana
    2. Take the bus from Los Angeles Union Station to San Luis Obispo Railroad Museumbus bus FlixBus 2005
    7h 55m
    $53–89
  3. Train (Amtrak)

    1. Take the train from San Diego to San Luis Obispotrain train Pacific Surfliner
    8h 36m
    $100–230
  4. Drive 305.6 mi

    1. Drive from San Diego to San Luis Obispocar car 305.6 mi
    5h 33m
    $56–81

San Diego to San Luis Obispo by bus

Calendar4Weekly Buses
Duration7h 55mAverage Duration
Ticket$53Cheapest Price
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Questions & Answers

What companies run services between San Diego, CA, USA and San Luis Obispo, CA, USA?

Alaska Airlines, Inc. and United Airlines fly from San Diego International Airport (SAN) to San Luis Obispo County Regional Airport (SBP) twice daily. Alternatively, you can take a bus from San Diego to San Luis Obispo Railroad Museum via Los Angeles Union Station in around 7h 55m.

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