There are 4 ways to get from San Diego to San Luis Obispo by plane, bus (Greyhound, Flixbus), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from San Diego International Airport (SAN) to San Luis Obispo County Regional Airport (SBP)plane SAN - SBP
2h 24m$171–344Bus
cheapest- Take the bus from San Diego to Los Angeles Union Stationbus Tijuana
- Take the bus from Los Angeles Union Station to San Luis Obispo Railroad Museumbus FlixBus 2005
7h 55m$53–89Train (Amtrak)
- Take the train from San Diego to San Luis Obispotrain Pacific Surfliner
8h 36m$100–230Drive 305.6 mi
- Drive from San Diego to San Luis Obispocar 305.6 mi
5h 33m$56–81
San Diego to San Luis Obispo by bus
Questions & Answers
The cheapest way to get from San Diego to San Luis Obispo is to drive which costs $55 - $85 and takes 5h 33m.
The fastest way to get from San Diego to San Luis Obispo is to fly which takes 2h 24m and costs $170 - $350.
No, there is no direct bus from San Diego to San Luis Obispo. However, there are services departing from San Diego and arriving at San Luis Obispo Railroad Museum via Los Angeles Union Station. The journey, including transfers, takes approximately 7h 55m.
Yes, there is a direct train departing from San Diego and arriving at San Luis Obispo. Services depart twice daily, and operate every day. The journey takes approximately 8h 36m.
The distance between San Diego and San Luis Obispo is 268 miles. The road distance is 307.4 miles.
The best way to get from San Diego to San Luis Obispo without a car is to bus which takes 7h 55m and costs $50 - $90.
It takes approximately 2h 24m to get from San Diego to San Luis Obispo, including transfers.
San Diego to San Luis Obispo bus services, operated by Greyhound Mexico, depart from San Diego station.
San Diego to San Luis Obispo train services, operated by Amtrak, depart from San Diego station.
The best way to get from San Diego to San Luis Obispo is to fly which takes 2h 24m and costs $170 - $350. Alternatively, you can bus, which costs $50 - $90 and takes 7h 55m, you could also train, which costs $100 - $230 and takes 8h 36m.
What companies run services between San Diego, CA, USA and San Luis Obispo, CA, USA?
Alaska Airlines, Inc. and United Airlines fly from San Diego International Airport (SAN) to San Luis Obispo County Regional Airport (SBP) twice daily. Alternatively, you can take a bus from San Diego to San Luis Obispo Railroad Museum via Los Angeles Union Station in around 7h 55m.
- Website
- alaskaair.com
Flights from San Diego International Airport to San Luis Obispo County Regional Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $170–350
- Website
- united.com
Flights from San Diego International Airport to San Luis Obispo County Regional Airport via Los Angeles
- Ave. Duration
- 2h 58m
- When
- Wednesday
- Estimated price
- $30–200
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Diego to San Luis Obispo
- Ave. Duration
- 8h 36m
- Frequency
- Twice daily
- Estimated price
- $100–230
- Website
- Amtrak
- Phone
- +1-800-231-2222
- [email protected]
- Website
- Greyhound Mexico
Bus from San Diego to Los Angeles Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $24–40
- Schedules at
- Greyhound Mexico
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Los Angeles Union Station to San Luis Obispo Railroad Museum
- Ave. Duration
- 4h
- Frequency
- 4 times a week
- Estimated price
- $29–50
- Schedules at
- Flixbus USA
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More Questions & Answers
San Diego to San Luis Obispo bus services, operated by Greyhound Mexico, arrive at Los Angeles Union Station.
San Diego to San Luis Obispo train services, operated by Amtrak, arrive at San Luis Obispo station.
Yes, the driving distance between San Diego to San Luis Obispo is 307 miles. It takes approximately 5h 33m to drive from San Diego to San Luis Obispo.
Book your San Diego to San Luis Obispo train tickets online with Omio.
Book your San Diego to San Luis Obispo bus tickets online with Omio.
There are 261+ hotels available in San Luis Obispo.












