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How to get fromSan Diego to Sanibelby plane, bus (Amtrak, Greyhound), train, bus, car, or taxi

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There are 8 ways to get from San Diego to Sanibel by plane, bus (Amtrak, Greyhound), train, bus, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Ft. Myers

    best
    1. Fly from San Diego International Airport (SAN) to Ft. Myers (RSW)plane plane SAN - RSW
    7h 42m
    $253–787

  2. Bus via Santa Ana

    1. Take the bus from San Diego to Santa Anabus bus
    2. Take the bus from Santa Ana to El Pasobus bus Cbx
    3. Take the bus from El Paso Bus Station to Houston Bus Stationbus bus
    4. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    2d 9h
    $481–733

  3. Train, bus

    1. Take the train from San Diego to Los Angelestrain train
    2. Take the train from Los Angeles to Houstontrain train
    3. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    2d 13h
    $774–1,486

  4. Drive 2,546 mi

    1. Drive from San Diego to Sanibelcar car 2,546 mi
    41h 8m
    $465–672

  5. Fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from San Diego International Airport (SAN) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane SAN - FLL
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    8h 48m
    $377–1,277

  6. Fly to Miami International Airport, bus, taxi

    1. Fly from San Diego International Airport (SAN) to Miami International Airport (MIA)plane plane SAN - MIA
    2. Take the bus from Miami Airport to Fort Myers 7-11bus bus
    3. Take the taxi from Fort Myers 7-11 to Sanibeltaxi taxi
    9h 35m
    $264–641

  7. Fly to Sarasota–Bradenton International Airport, bus

    1. Fly from San Diego International Airport (SAN) to Sarasota–Bradenton International Airport (SRQ)plane plane SAN - SRQ
    2. Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus bus
    10h 57m
    $291–953

  8. Bus

    1. Take the bus from Cross Border Express, San Diego to El Pasobus bus Cbx
    2. Take the bus from El Paso, TX - Tornado Bus Co to Houston, TX - Houston Airline Drbus bus
    3. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    2d 17h
    $490–766

San Diego International Airport (SAN) to Ft. Myers (RSW) flights

Calendar55Weekly Planes
Duration8h 48mAverage Duration
Ticket$177Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Sanibel.ExpandLaunch map view
  • Distance: 2,185.7 mi
  • Duration: 7h 42m

What companies run services between San Diego, CA, USA and Sanibel, FL, USA?

American Airlines, Delta, and Southwest Airlines fly from San Diego International Airport (SAN) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from San Diego to Sanibel via Santa Ana, El Paso, El Paso Bus Station, Houston Bus Station, Houston - Harrisburg Blvd, and Fort Myers in around 2d 9h.

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