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How to get fromSan Diego to Sanibel Islandby plane, bus (Amtrak, Greyhound), bus, train, or car

Find Transport to Sanibel Island

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There are 6 ways to get from San Diego to Sanibel Island by plane, bus (Amtrak, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Ft. Myers

    best
    1. Fly from San Diego International Airport (SAN) to Ft. Myers (RSW)plane plane SAN - RSW
    7h 40m
    $244–771

  2. Fly to Miami International Airport, bus

    cheapest
    1. Fly from San Diego International Airport (SAN) to Miami International Airport (MIA)plane plane SAN - MIA
    2. Take the bus from Miami Airport to Fort Myers 7-11bus bus
    9h 33m
    $240–641

  3. Bus

    1. Take the bus from San Diego to Santa Anabus bus
    2. Take the bus from Santa Ana to El Pasobus bus Cbx
    3. Take the bus from El Paso Bus Station to Houston Bus Stationbus bus
    4. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    2d 9h
    $481–728

  4. Bus, train

    1. Take the bus from El Cajon Transit Center to Yuma County Area Transitbus bus
    2. Take the train from Yuma Amtrak to Houstontrain train
    3. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    2d 12h
    $680–1,264

  5. Drive 2,545 mi

    1. Drive from San Diego to Sanibel Islandcar car 2,545 mi
    41h 6m
    $465–671

  6. Fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from San Diego International Airport (SAN) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane SAN - FLL
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    8h 45m
    $371–1,126

San Diego International Airport (SAN) to Ft. Myers (RSW) flights

Calendar55Weekly Planes
Duration8h 48mAverage Duration
Ticket$168Cheapest Price
See schedules

Questions & Answers

Map of how to get from San Diego to Sanibel Island.ExpandLaunch map view
  • Distance: 2,184.7 mi
  • Duration: 7h 40m

What companies run services between San Diego, CA, USA and Sanibel Island, FL, USA?

American Airlines, Delta, and Southwest Airlines fly from San Diego International Airport (SAN) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from San Diego to Sanibel Island via Santa Ana, El Paso, El Paso Bus Station, Houston Bus Station, Houston - Harrisburg Blvd, and Fort Myers in around 2d 9h.

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Train operators
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