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How to get fromSan Diego to South Carolinaby plane, train (Amtrak), car, or taxi

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There are 6 ways to get from San Diego to South Carolina by plane, train (Amtrak), car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport

    best
    1. Fly from San Diego International Airport (SAN) to Greenville–Spartanburg International Airport (GSP)plane plane SAN - GSP
    6h 23m
    $242–894

  2. Fly to Columbia

    cheapest
    1. Fly from San Diego International Airport (SAN) to Columbia (CAE)plane plane SAN - CAE
    7h 56m
    $148–594

  3. Train (Amtrak)

    1. Take the train from San Diego to Fullerton Amtrak Stationtrain train
    2. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    4. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    3d 3h
    $1,102–2,447

  4. Drive 2,426.4 mi

    1. Drive from San Diego to Charlestoncar car 2,426.4 mi
    38h 45m
    $443–640

  5. Fly to Charlotte Douglas International Airport, taxi

    1. Fly from San Diego International Airport (SAN) to Charlotte Douglas International Airport (CLT)plane plane SAN - CLT
    2. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    5h 22m
    $294–972

  6. Fly to Charleston International Airport

    1. Fly from San Diego International Airport (SAN) to Charleston International Airport (CHS)plane plane SAN - CHS
    7h 37m
    $566–977

San Diego International Airport (SAN) to Greenville–Spartanburg International Airport (GSP) flights

Calendar84Weekly Planes
Duration7h 25mAverage Duration
Ticket$207Cheapest Price
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Questions & Answers

Map of how to get from San Diego to South Carolina.ExpandLaunch map view
  • Distance: 2,015.8 mi
  • Duration: 6h 23m

What companies run services between San Diego, CA, USA and South Carolina, USA?

Southwest Airlines, American Airlines, and two other airlines fly from San Diego International Airport (SAN) to Greenville–Spartanburg International Airport (GSP) every 2 hours. Alternatively, you can take a train from San Diego to Charleston via Fullerton Amtrak Station, Chicago Union Station, Petersburg Amtrak Station, and Charleston Amtrak Station in around 3d 3h.

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