There are 9 ways to get from San Diego to Tupelo by plane, car, bus (Greyhound, Flixbus), train, bus, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Golden Triangle Regional Airport, drive
best- Fly from San Diego International Airport (SAN) to Golden Triangle Regional Airport (GTR)plane SAN - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
7h 23m$106–432Bus via Phoenix
- Take the bus from San Diego Greyhound Bus Stop to Phoenix Bus Stationbus
- Take the bus from Phoenix Bus Station to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
43h$359–559Train, bus via Kansas City
- Take the train from San Diego to Fullerton Amtrak Stationtrain
- Take the train from Fullerton Amtrak Station to Kansas Citytrain
- Take the train from Kansas City to St. Louistrain
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
2d 5h$1,229–1,947Drive 1,871.2 mi
- Drive from San Diego to Tupelocar 1,871.2 mi
30h 6m$342–494Fly to Memphis, bus
- Fly from San Diego International Airport (SAN) to Memphis (MEM)plane SAN - MEM
- Take the bus from Memphis Bus Station to Tupelobus
9h 17m$215–862Fly to Tupelo Regional Airport
- Fly from San Diego International Airport (SAN) to Tupelo Regional Airport (TUP)plane SAN - TUP
5h 56m$139–561Bus
- Take the bus from San Diego to Los Angeles Union Stationbus
- Take the bus from Los Angeles Union Station to Tulsa Bus Stationbus
- Take the bus from Tulsa to Memphisbus
- Take the bus from Memphis Bus Station to Tupelobus
2d$418–620Train, bus
- Take the train from San Diego to Los Angelestrain
- Take the train from Los Angeles to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Jacksontrain
- Take the bus from Jackson to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
2d 13h$1,233–2,068Train, bus #2
- Take the train from San Diego to Los Angelestrain
- Take the train from Los Angeles to St. Louistrain
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
2d 20h$1,443–2,328
San Diego International Airport (SAN) to Golden Triangle Regional Airport (GTR) flights
Comparing Your Travel Options
The cheapest way to get from San Diego to Tupelo is to fly and drive which costs $100 - $440 and takes 7h 23m.
The fastest way to get from San Diego to Tupelo is to fly which takes 5h 56m and costs $130 - $600.
No, there is no direct bus from San Diego to Tupelo. However, there are services departing from San Diego Greyhound Bus Stop and arriving at Tupelo via Phoenix Bus Station, Dallas Bus Station and Memphis Bus Station. The journey, including transfers, takes approximately 43h.
The distance between San Diego and Tupelo is 1724 miles. The road distance is 1882.1 miles.
The best way to get from San Diego to Tupelo without a car is to bus via Phoenix which takes 43h and costs $350 - $600.
It takes approximately 7h 23m to get from San Diego to Tupelo, including transfers.
San Diego to Tupelo bus services, operated by Greyhound USA, depart from San Diego Greyhound Bus Stop station.
The best way to get from San Diego to Tupelo is to bus via Phoenix which takes 43h and costs $350 - $600. Alternatively, you can fly, which costs $130 - $600 and takes 5h 56m.
San Diego to Tupelo bus services, operated by Greyhound USA, arrive at Phoenix Bus Station.
Tupelo is 2h ahead of San Diego. It is currently 2:37 AM in San Diego and 4:37 AM in Tupelo.
What companies run services between San Diego, CA, USA and Tupelo, MS, USA?
You can take a vehicle from County Center/Little Italy Station to Tupelo via Old Town Station, San Diego Greyhound Bus Stop, Phoenix Bus Station, Dallas Bus Station, Memphis Bus Station, and Tupelo in around 43h. Alternatively, American Airlines, Corporate Flight Management Inc, and Southwest Airlines fly from San Diego International Airport (SAN) to Tupelo Regional Airport (TUP) 3 times a day.
- Website
- southwest.com
Flights from San Diego International Airport to Memphis via Phoenix
- Ave. Duration
- 5h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $180–850
Flights from San Diego International Airport to Memphis via Dallas
- Ave. Duration
- 5h 27m
- When
- Monday to Wednesday
- Estimated price
- $180–850
Flights from San Diego International Airport to Memphis via Denver
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $200–900
Flights from San Diego International Airport to Memphis via Austin
- Ave. Duration
- 6h 20m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $200–900
Flights from San Diego International Airport to Memphis via Houston Hobby Apt
- Ave. Duration
- 6h 37m
- When
- Tuesday to Friday
- Estimated price
- $200–900
- Website
- aa.com
Flights from San Diego International Airport to Golden Triangle Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $95–420
Flights from San Diego International Airport to Memphis via Phoenix
- Ave. Duration
- 5h 24m
- When
- Tuesday and Saturday
- Estimated price
- $180–850
Flights from San Diego International Airport to Memphis via Dallas/Ft.Worth
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $180–850
- Website
- contouraviation.com
Flights from San Diego International Airport to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $120–550
Flights from San Diego International Airport to Tupelo Regional Airport via Nashville
- Ave. Duration
- 10h 52m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- $140–600
Flights from San Diego International Airport to Tupelo Regional Airport via Phoenix, Dallas/Ft.Worth
- Ave. Duration
- 7h 39m
- When
- Monday, Tuesday, Thursday, and Saturday
- Estimated price
- $120–550
Flights from San Diego International Airport to Tupelo Regional Airport via Albuquerque, Nashville
- Ave. Duration
- 8h 15m
- When
- Sunday
- Estimated price
- $140–600
- Website
- united.com
Flights from San Diego International Airport to Memphis via Houston
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $200–900
Flights from San Diego International Airport to Memphis via Denver
- Ave. Duration
- 5h 55m
- When
- Every day
- Estimated price
- $200–900
- Website
- delta.com
Flights from San Diego International Airport to Golden Triangle Regional Airport via Atlanta
- Ave. Duration
- 7h 23m
- When
- Every day
- Estimated price
- $110–480
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Diego to Fullerton Amtrak Station
- Ave. Duration
- 2h 19m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
Train from Fullerton Amtrak Station to Kansas City
- Ave. Duration
- 34h 31m
- Frequency
- Once daily
- Estimated price
- $950–1,500
- Website
- Amtrak
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $150–240
- Website
- Amtrak
Train from San Diego to Los Angeles
- Ave. Duration
- 2h 56m
- Frequency
- Hourly
- Estimated price
- $70–110
- Website
- Amtrak
Train from Los Angeles to New Orleans Union Passenger Terminal
- Ave. Duration
- 45h 40m
- Frequency
- 3 times a week
- Estimated price
- $1,000–1,700
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Jackson
- Ave. Duration
- 3h 39m
- Frequency
- Once daily
- Estimated price
- $100–160
- Website
- Amtrak
Train from San Diego to Los Angeles
- Ave. Duration
- 2h 56m
- Frequency
- Hourly
- Estimated price
- $70–110
- Website
- Amtrak
Train from Los Angeles to St. Louis
- Ave. Duration
- 2d 7h
- Frequency
- 3 times a week
- Estimated price
- $1,300–2,100
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from San Diego Greyhound Bus Stop to Phoenix Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Once daily
- Estimated price
- $65–100
- Website
- Greyhound
Bus from Phoenix Bus Station to Dallas Bus Station
- Ave. Duration
- 20h 55m
- Frequency
- Twice daily
- Estimated price
- $190–290
- Website
- Greyhound
Bus from Dallas Bus Station to Memphis Bus Station
- Ave. Duration
- 8h 44m
- Frequency
- 4 times a day
- Estimated price
- $85–130
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $17–27
- Website
- Greyhound
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $17–27
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $17–27
- Website
- Greyhound
Bus from Los Angeles Union Station to Tulsa Bus Station
- Ave. Duration
- 32h 35m
- Frequency
- Once daily
- Estimated price
- $270–400
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $17–27
- Website
- Greyhound
Bus from Jackson to Memphis Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $17–27
- Website
- Greyhound
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $17–27
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Dallas Bus Station to Memphis Bus Station
- Ave. Duration
- 8h
- Frequency
- 5 times a week
- Estimated price
- $75–120
- Schedules at
- Flixbus USA
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- 5 times a week
- Estimated price
- $45–70
- Schedules at
- Flixbus USA
Bus from San Diego to Los Angeles Union Station
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- $19–29
- Schedules at
- Flixbus USA
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- 5 times a week
- Estimated price
- $45–70
- Schedules at
- Flixbus USA
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Tulsa to Memphis
- Ave. Duration
- 8h 35m
- Frequency
- 4 times a week
- Estimated price
- $100–150
- Book at
- Jefferson Lines
- Adult
- $100–150
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between San Diego to Tupelo is 1882 miles. It takes approximately 30h 6m to drive from San Diego to Tupelo.
Book your San Diego to Tupelo bus tickets online with Omio.
There are 26+ hotels available in Tupelo.












