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How to get fromSan Diego to Winston-Salemby plane, bus (Greyhound), bus, train, car, or train (Amtrak)

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There are 7 ways to get from San Diego to Winston-Salem by plane, bus (Greyhound), bus, train, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from San Diego International Airport (SAN) to Piedmont Triad International Airport (GSO)plane plane SAN - GSO
    7h 52m
    $281–1,047

  2. Fly to Raleigh-Durham International Airport, bus

    cheapest
    1. Fly from San Diego International Airport (SAN) to Raleigh-Durham International Airport (RDU)plane plane SAN - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    9h 8m
    $206–835

  3. Bus (Greyhound)

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    2d 11h
    $399–784

  4. Bus, train

    1. Take the bus from San Diego to Fullerton Amtrak Stationbus bus
    2. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago to Columbus - Mound Stbus bus
    4. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    2d 17h
    $825–1,749

  5. Drive 2,392.3 mi

    1. Drive from San Diego to Winston-Salemcar car 2,392.3 mi
    39h 32m
    $437–631

  6. Fly to Charlotte Douglas International Airport, bus

    1. Fly from San Diego International Airport (SAN) to Charlotte Douglas International Airport (CLT)plane plane SAN - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    8h 1m
    $243–959

  7. Train (Amtrak)

    1. Take the train from San Diego to Los Angelestrain train
    2. Take the train from Los Angeles to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to High Pointtrain train
    3d 1h
    $912–2,088

San Diego to Winston-Salem by bus (Greyhound)

Calendar21Weekly Buses
Duration2d 11hAverage Duration
Ticket$399Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Winston-Salem.ExpandLaunch map view
  • Distance: 2,146.7 mi
  • Duration: 7h 52m

What companies run services between San Diego, CA, USA and Winston-Salem, NC, USA?

Delta, American Airlines, and United Airlines fly from San Diego International Airport (SAN) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from San Diego to Winston Salem(Trans Center) via Los Angeles Union Station, Dallas Bus Station, and Atlanta Bus Station in around 2d 11h.

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