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How to get fromSan Francisco to Des Moinesby plane, bus (Greyhound), train, bus, or car

Find Transport to Des Moines

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There are 7 ways to get from San Francisco to Des Moines by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from San Francisco International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to Des Moines (DSM)plane plane SFO - DSM
    6h 58m
    $217–683

  2. Bus

    1. Take the bus from San Francisco Bus Station to Sparks Transit Centerbus bus
    2. Take the bus from Sparks Transit Center to Denver Union Stationbus bus
    3. Take the bus from Denver to Des Moinesbus bus
    40h 54m

  3. Train, bus

    1. Take the train from Richmond to Denvertrain train California Zephyr
    2. Take the bus from Denver to Des Moinesbus bus Btw 1402
    47h 22m

  4. Drive 1,795.5 mi

    1. Drive from San Francisco to Des Moinescar car 1,795.5 mi
    27h 23m
    $328–474

  5. Fly from Oakland International Airport

    1. Fly from Oakland International Airport (OAK) to Des Moines (DSM)plane plane OAK - DSM
    6h 57m
    $243–979

  6. Caltrain to Norman Y. Mineta San José International Airport, fly

    1. Take the train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Des Moines (DSM)plane plane SJC - DSM
    8h 11m
    $229–935

  7. Train, bus via Omaha

    1. Take the train from Richmond to Denvertrain train
    2. Take the bus from Denver to Omaha, NEbus bus
    3. Take the bus from Omaha to Des Moinesbus bus
    2d

San Francisco International Airport (SFO) to Des Moines (DSM) flights

Calendar73Weekly Planes
Duration6h 31mAverage Duration
Ticket$184Cheapest Price
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Questions & Answers

Map of how to get from San Francisco to Des Moines.ExpandLaunch map view
  • Distance: 1,567.4 mi
  • Duration: 6h 58m

What companies run services between San Francisco, CA, USA and Des Moines, IA, USA?

Southwest Airlines, United Airlines, and three other airlines fly from San Francisco International Airport (SFO) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from San Francisco Bus Station to Des Moines via Sparks Transit Center, Denver Union Station, and Denver in around 40h 54m.

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