Rome2Rio

How to get fromSan Francisco to Florida Keysby plane, train, bus, car, shuttle, or ferry

Find Transport to Florida Keys

See all options

There are 8 ways to get from San Francisco to Florida Keys by plane, train, bus, car, shuttle, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Francisco International Airport to Key West International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to Key West International Airport (EYW)plane plane SFO - EYW
    12h 19m
    $227–656

  2. Train, bus

    1. Take the train from Richmond to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4d 11h
    $1,461–3,089

  3. Drive 3,143.7 mi

    1. Drive from San Francisco to Florida Keyscar car 3,143.7 mi
    2d 5h
    $574–829

  4. Caltrain to Norman Y. Mineta San José International Airport, fly to Key West International Airport

    1. Take the train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Key West International Airport (EYW)plane plane SJC - EYW
    13h 17m
    $249–708

  5. Fly San Francisco International Airport to Miami International Airport, shuttle

    1. Fly from San Francisco International Airport (SFO) to Miami International Airport (MIA)plane plane SFO - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    12h 32m
    $322–586

  6. Fly San Francisco International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from San Francisco International Airport (SFO) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane SFO - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    13h 7m
    $432–1,166

  7. Train to Sacramento International Airport, fly to Key West International Airport

    1. Take the train from Richmond to Sacramentotrain train
    2. Fly from Sacramento International Airport (SMF) to Key West International Airport (EYW)plane plane SMF - EYW
    14h 58m
    $280–858

  8. Fly San Francisco International Airport to Ft. Myers, ferry

    1. Fly from San Francisco International Airport (SFO) to Ft. Myers (RSW)plane plane SFO - RSW
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    15h 22m
    $346–892

San Francisco to Florida Keys by subway, train, taxi, bus, and foot

Calendar7Weekly Services
Duration4d 11hAverage Duration
Ticket$1,461Cheapest Price
See schedules

Questions & Answers

Map of how to get from San Francisco to Florida Keys.ExpandLaunch map view
  • Distance: 2,579.9 mi
  • Duration: 12h 19m

What companies run services between San Francisco, CA, USA and Florida Keys, FL, USA?

American Airlines and Delta fly from San Francisco International Airport (SFO) to Key West International Airport (EYW) every 4 hours.

Airlines
Train operators
Bus operators
Ferry operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound