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How to get fromSan Francisco to Florida Keysby plane, train, bus, car, shuttle, or ferry

Find Transport to Florida Keys

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There are 8 ways to get from San Francisco to Florida Keys by plane, train, bus, car, shuttle, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Francisco International Airport to Key West International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to Key West International Airport (EYW)plane plane SFO - EYW
    12h 13m
    $197–556

  2. Train, bus

    1. Take the train from Richmond to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4d 11h
    $2,448–3,969

  3. Drive  3,143.3 mi

    1. Drive from San Francisco to Florida Keyscar car 3,143.3 mi
    2d 5h
    $574–829

  4. Caltrain to Norman Y. Mineta San José International Airport, fly to Key West International Airport

    1. Take the train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Key West International Airport (EYW)plane plane SJC - EYW
    13h 12m
    $219–658

  5. Fly San Francisco International Airport to Miami International Airport, shuttle

    1. Fly from San Francisco International Airport (SFO) to Miami International Airport (MIA)plane plane SFO - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    12h 21m
    $332–586

  6. Fly San Francisco International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from San Francisco International Airport (SFO) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane SFO - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    12h 51m
    $322–816

  7. Train to Sacramento International Airport, fly to Key West International Airport

    1. Take the train from Richmond to Sacramentotrain train
    2. Fly from Sacramento International Airport (SMF) to Key West International Airport (EYW)plane plane SMF - EYW
    15h 7m
    $254–724

  8. Fly San Francisco International Airport to Ft. Myers, ferry

    1. Fly from San Francisco International Airport (SFO) to Ft. Myers (RSW)plane plane SFO - RSW
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    15h 22m
    $336–842

San Francisco to Florida Keys by subway, train, taxi, bus, and foot

Calendar7Weekly Services
Duration4d 11hAverage Duration
Ticket$2,448Cheapest Price
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Comparing Your Travel Options

Map of how to get from San Francisco to Florida Keys.ExpandLaunch map view
  • Distance: 2,579.9 mi
  • Duration: 12h 13m

What companies run services between San Francisco, CA, USA and Florida Keys, FL, USA?

American Airlines, Delta, and United Airlines fly from San Francisco International Airport (SFO) to Key West International Airport (EYW) every 4 hours.

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