Rome2Rio

How to get fromSan Francisco to Greenvilleby plane, bus (Flixbus, Greyhound), train, bus, or car

Find Transport to Greenville

See all options

There are 7 ways to get from San Francisco to Greenville by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from San Francisco International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to Greenville–Spartanburg International Airport (GSP)plane plane SFO - GSP
    8h 28m
    $255–907

  2. Bus

    1. Take the bus from San Francisco to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    2d 15h
    $460–929

  3. Train, bus

    1. Take the train from Richmond to Chicago Union Stationtrain train
    2. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    3d 4h
    $868–1,988

  4. Drive 2,598.5 mi

    1. Drive from San Francisco to Greenvillecar car 2,598.5 mi
    41h 42m
    $475–685

  5. Fly from Oakland International Airport

    1. Fly from Oakland International Airport (OAK) to Greenville–Spartanburg International Airport (GSP)plane plane OAK - GSP
    10h 4m
    $281–1,053

  6. Caltrain to Norman Y. Mineta San José International Airport, fly

    1. Take the train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Greenville–Spartanburg International Airport (GSP)plane plane SJC - GSP
    9h 38m
    $277–1,059

  7. Train, bus via Chicago

    1. Take the train from Richmond to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    3d 4h
    $868–1,988

San Francisco International Airport (SFO) to Greenville–Spartanburg International Airport (GSP) flights

Calendar79Weekly Planes
Duration7h 59mAverage Duration
Ticket$210Cheapest Price
See schedules

Questions & Answers

Map of how to get from San Francisco to Greenville.ExpandLaunch map view
  • Distance: 2,255.3 mi
  • Duration: 8h 28m

What companies run services between San Francisco, CA, USA and Greenville, SC, USA?

Delta, American Airlines, and two other airlines fly from San Francisco International Airport (SFO) to Greenville–Spartanburg International Airport (GSP) every 2 hours. Alternatively, you can take a bus from San Francisco to Greenville via Los Angeles Union Station, Dallas Bus Station, Atlanta Bus Station, Garnett Station, Lindbergh Center Station, Lindbergh Center Station - Bay D, Shallowford Rd @ New Peachtree, Atlanta, and Taqueria Guadalajara - Greenville in around 2d 15h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers