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How to get fromSan Francisco to Guayaquilby plane or bus

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There are 4 ways to get from San Francisco to Guayaquil by plane or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Francisco International Airport to José Joaquín De Olmedo International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to José Joaquín De Olmedo International Airport (GYE)plane plane SFO - GYE
    12h 50m
    $220–762

  2. Fly San Francisco International Airport to Cuenca, bus

    cheapest
    1. Fly from San Francisco International Airport (SFO) to Cuenca (CUE)plane plane SFO - CUE
    2. Take the bus from Cuenca to Terminal Terrestre de Guayaquilbus bus
    18h 59m
    $210–722

  3. Fly San Francisco International Airport to Eloy Alfaro International Airport, bus

    1. Fly from San Francisco International Airport (SFO) to Eloy Alfaro International Airport (MEC)plane plane SFO - MEC
    2. Take the bus from Manta to Terminal Terrestre de Guayaquilbus bus
    20h 50m
    $227–777

  4. Fly Oakland International Airport to José Joaquín De Olmedo International Airport

    1. Fly from Oakland International Airport (OAK) to José Joaquín De Olmedo International Airport (GYE)plane plane OAK - GYE
    17h 56m
    $376–858

San Francisco International Airport (SFO) to José Joaquín De Olmedo International Airport (GYE) flights

Calendar30Weekly Planes
Duration13h 50mAverage Duration
Ticket$212Cheapest Price
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Questions & Answers

Map of how to get from San Francisco to Guayaquil.ExpandLaunch map view
  • Distance: 6,237.8 km
  • Duration: 12h 50m

What companies run services between San Francisco, CA, USA and Guayaquil, Ecuador?

Copa Airlines, American Airlines, and two other airlines fly from San Francisco International Airport (SFO) to José Joaquín De Olmedo International Airport (GYE) 4 times a day.

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Bus operators

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