Rome2Rio

How to get fromSan Francisco to Key Largoby plane, shuttle, bus (Flixbus, Greyhound), train, or car

Find Transport to Key Largo

See all options

There are 8 ways to get from San Francisco to Key Largo by plane, shuttle, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Francisco International Airport to Miami International Airport, shuttle

    best
    1. Fly from San Francisco International Airport (SFO) to Miami International Airport (MIA)plane plane SFO - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    9h 6m
    $280–532

  2. Fly Oakland International Airport to Miami International Airport, shuttle

    cheapest
    1. Fly from Oakland International Airport (OAK) to Miami International Airport (MIA)plane plane OAK - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    10h 49m
    $266–838

  3. Bus

    1. Take the bus from San Francisco to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    3d 1h
    $508–833

  4. Train, shuttle

    1. Take the train from Richmond to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    4d 7h
    $1,179–2,765

  5. Drive  3,061.5 mi

    1. Drive from San Francisco to Key Largocar car 3,061.5 mi
    2d 3h
    $559–807

  6. Fly San Francisco International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from San Francisco International Airport (SFO) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane SFO - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    9h 37m
    $390–1,112

  7. Fly Oakland International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Oakland International Airport (OAK) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane OAK - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    11h 11m
    $296–908

  8. Caltrain to Norman Y. Mineta San José International Airport, fly to Miami International Airport, shuttle

    1. Take the train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Miami International Airport (MIA)plane plane SJC - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    12h 10m
    $272–844

San Francisco to Key Largo by bus

Calendar9Weekly Buses
Duration3d 1hAverage Duration
Ticket$508Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from San Francisco to Key Largo.ExpandLaunch map view
  • Distance: 2,653.3 mi
  • Duration: 9h 6m

What companies run services between San Francisco, CA, USA and Key Largo, FL, USA?

You can take a bus from San Francisco to Key Largo Bus Stop via Los Angeles Union Station, Dallas Bus Station, Atlanta Bus Station, and Miami Airport Station in around 3d 1h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There