There are 8 ways to get from San Francisco to Key West (Island) by plane, bus (Flixbus, Greyhound), train, bus, ferry, car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly San Francisco International Airport to Key West International Airport
best- Fly from San Francisco International Airport (SFO) to Key West International Airport (EYW)plane SFO - EYW
9h 28m$140–562Bus
- Take the bus from San Francisco to Los Angeles Union Stationbus
- Take the bus from Los Angeles Union Station to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key West Airportbus
3d 6h$532–1,020Train, bus, ferry
- Take the train from Oakland to Los Angelestrain
- Take the train from Los Angeles to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain
- Take the bus from Gulfport to Fort Myersbus
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry
3d 9h$1,124–2,099Drive 3,159.1 mi
- Drive from San Francisco to Key Westcar 3,159.1 mi
2d 5h$577–833Caltrain to Norman Y. Mineta San José International Airport, fly to Key West International Airport
- Take the train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southboundtrain
- Fly from Norman Y. Mineta San José International Airport (SJC) to Key West International Airport (EYW)plane SJC - EYW
10h 25m$162–614Fly San Francisco International Airport to Miami International Airport, shuttle
- Fly from San Francisco International Airport (SFO) to Miami International Airport (MIA)plane SFO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key West, FL
12h 2m$350–602Train to Sacramento International Airport, fly to Key West International Airport
- Take the train from Richmond to Sacramentotrain
- Fly from Sacramento International Airport (SMF) to Key West International Airport (EYW)plane SMF - EYW
12h 9m$192–715Train, bus
- Take the train from Richmond to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key West Airportbus
4d 11h$1,431–3,057
San Francisco to Key West (Island) by bus
Questions & Answers
The cheapest way to get from San Francisco to Key West (Island) is to fly which costs $140 - $600 and takes 9h 28m.
The fastest way to get from San Francisco to Key West (Island) is to fly which takes 9h 28m and costs $140 - $600.
No, there is no direct bus from San Francisco to Key West (Island). However, there are services departing from San Francisco and arriving at Key West Airport via Los Angeles Union Station, Dallas Bus Station, Atlanta Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 3 days 6h.
The distance between San Francisco and Key West (Island) is 2574 miles. The road distance is 3177.6 miles.
The best way to get from San Francisco to Key West (Island) without a car is to bus which takes 3 days 6h and costs $500 - $1,100.
It takes approximately 9h 28m to get from San Francisco to Key West (Island), including transfers.
San Francisco to Key West (Island) bus services, operated by Flixbus USA, depart from San Francisco station.
The best way to get from San Francisco to Key West (Island) is to fly which takes 9h 28m and costs $140 - $600. Alternatively, you can bus, which costs $500 - $1,100 and takes 3 days 6h.
San Francisco to Key West (Island) bus services, operated by Flixbus USA, arrive at Los Angeles Union Station.
Key West (Island) is 3h ahead of San Francisco. It is currently 2:56 PM in San Francisco and 5:56 PM in Key West (Island).
What companies run services between San Francisco, CA, USA and Key West (Island), FL, USA?
American Airlines and Delta fly from San Francisco International Airport (SFO) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from San Francisco to Key West Airport via Los Angeles Union Station, Dallas Bus Station, Atlanta Bus Station, and Miami Airport Station in around 3d 6h.
- Website
- aa.com
Flights from San Francisco International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 8h 35m
- When
- Every day
- Estimated price
- $140–550
Flights from San Francisco International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 22m
- When
- Every day
- Estimated price
- $130–550
Flights from San Francisco International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 10h 13m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $150–600
Flights from Norman Y. Mineta San José International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 52m
- When
- Every day
- Estimated price
- $150–600
Flights from San Francisco International Airport to Miami International Airport
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $160–650
Flights from San Francisco International Airport to Miami International Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 6m
- When
- Every day
- Estimated price
- $160–650
Flights from Sacramento International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 8m
- When
- Every day
- Estimated price
- $160–650
Flights from Sacramento International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 11h 24m
- When
- Every day
- Estimated price
- $190–750
- Website
- delta.com
Flights from San Francisco International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 8h 32m
- When
- Every day
- Estimated price
- $140–550
Flights from Norman Y. Mineta San José International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 8h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–650
Flights from Sacramento International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 9h 47m
- When
- Every day
- Estimated price
- $170–700
- Website
- united.com
Flights from San Francisco International Airport to Miami International Airport
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $160–650
Flights from San Francisco International Airport to Miami International Airport via Houston
- Ave. Duration
- 8h 49m
- When
- Every day
- Estimated price
- $160–650
Flights from Sacramento International Airport to Key West International Airport via Newark
- Ave. Duration
- 11h 41m
- When
- Every day
- Estimated price
- $230–850
- Website
- flyfrontier.com
Flights from San Francisco International Airport to Miami International Airport via Dallas/Ft.Worth
- Ave. Duration
- 10h 1m
- When
- Every day
- Estimated price
- $170–390
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Oakland to Los Angeles
- Ave. Duration
- 12h 2m
- Frequency
- Once daily
- Estimated price
- $150–310
- Website
- https://www.amtrak.com/home.html
Train from Los Angeles to New Orleans Union Passenger Terminal
- Ave. Duration
- 45h 40m
- Frequency
- 3 times a week
- Estimated price
- $650–1,400
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Gulfport Amtrak Sta
- Ave. Duration
- 59 min
- Frequency
- Twice daily
- Estimated price
- $21–45
- Website
- https://www.amtrak.com/home.html
Train from Richmond to Sacramento
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- $25–55
- Website
- https://www.amtrak.com/home.html
Train from Richmond to Chicago Union Station
- Ave. Duration
- 2d 4h
- Frequency
- Once daily
- Estimated price
- $750–1,600
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Hollywood Amtrak Station
- Ave. Duration
- 46h 6m
- Frequency
- Once daily
- Estimated price
- $650–1,400
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-660-4287
- Website
- caltrain.com
Train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southbound
- Ave. Duration
- 1h 11m
- Frequency
- Every 30 minutes
- Estimated price
- $9–12
- Website
- https://www.caltrain.com
- Schedules at
- https://www.caltrain.com/?active_tab=route_explorer_tab
- One-way Adult
- $9–12
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from San Francisco to Los Angeles Union Station
- Ave. Duration
- 9h 5m
- Frequency
- 4 times a week
- Estimated price
- $65–120
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Once daily
- Estimated price
- $110–190
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Los Angeles Union Station to Dallas Bus Station
- Ave. Duration
- 29h 5m
- Frequency
- Twice daily
- Estimated price
- $220–420
- Website
- https://www.greyhound.com/
Bus from Dallas Bus Station to Atlanta Bus Station
- Ave. Duration
- 18h 5m
- Frequency
- 3 times a day
- Estimated price
- $120–240
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $100–200
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Key West Airport
- Ave. Duration
- 4h 30m
- Frequency
- 3 times a day
- Estimated price
- $23–45
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Key West Airport
- Ave. Duration
- 4h 30m
- Frequency
- 3 times a day
- Estimated price
- $23–45
- Website
- https://www.greyhound.com/
- Phone
- +1 800-923-1799
- [email protected]
- Website
- omnibusexpress.com
Bus from Gulfport to Fort Myers
- Ave. Duration
- 13h 17m
- Frequency
- Once daily
- Estimated price
- $120–150
- Schedules at
- omnibusexpress.com
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key West, FL
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Yes, the driving distance between San Francisco to Key West (Island) is 3178 miles. It takes approximately 2 days 5h to drive from San Francisco to Key West (Island).
Book your San Francisco to Key West (Island) bus tickets online with FlixBus.
There are 979+ hotels available in Key West (Island).




















