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How to get fromSan Francisco to Louisvilleby plane, bus (Flixbus, Greyhound), train, bus, or car

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There are 7 ways to get from San Francisco to Louisville by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Francisco International Airport to Louisville International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to Louisville International Airport (SDF)plane plane SFO - SDF
    7h 8m
    $211–615

  2. Bus

    1. Take the bus from San Francisco to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Louisville, KYbus bus
    2d 10h
    $419–769

  3. Train, bus (Amtrak)

    1. Take the train from Richmond to Chicago Union Stationtrain train California Zephyr
    2. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    2d 13h
    $805–1,666

  4. Drive 2,306.6 mi

    1. Drive from San Francisco to Louisvillecar car 2,306.6 mi
    36h 4m
    $421–609

  5. Fly Oakland International Airport to Louisville International Airport

    1. Fly from Oakland International Airport (OAK) to Louisville International Airport (SDF)plane plane OAK - SDF
    8h 42m
    $237–961

  6. Caltrain to Norman Y. Mineta San José International Airport, fly to Louisville International Airport

    1. Take the train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Louisville International Airport (SDF)plane plane SJC - SDF
    10h 2m
    $233–917

  7. Fly San Francisco International Airport to Covington, bus

    1. Fly from San Francisco International Airport (SFO) to Covington (CVG)plane plane SFO - CVG
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    9h 54m
    $261–659

San Francisco to Louisville by bus

Calendar4Weekly Buses
Duration2d 10hAverage Duration
Ticket$419Cheapest Price
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Questions & Answers

Map of how to get from San Francisco to Louisville.ExpandLaunch map view
  • Distance: 2,005.2 mi
  • Duration: 7h 8m

What companies run services between San Francisco, CA, USA and Louisville, KY, USA?

Breeze Airways, Southwest Airlines, and three other airlines fly from San Francisco International Airport (SFO) to Louisville International Airport (SDF) every 3 hours. Alternatively, you can take a bus from San Francisco to Louisville, KY via Los Angeles Union Station, St Louis Bus Station, and Evansville, IN in around 2d 10h.

Airlines
Train operators
Bus operators

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