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How to get fromSan Francisco to Panamaby plane, bus (Flixbus), car, or train

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There are 6 ways to get from San Francisco to Panama by plane, bus (Flixbus), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Francisco International Airport to Tocumen International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to Tocumen International Airport (PTY)plane plane SFO - PTY
    10h 26m
    $460–652

  2. Caltrain to Norman Y. Mineta San José International Airport, fly to Tocumen International Airport

    cheapest
    1. Take the train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Tocumen International Airport (PTY)plane plane SJC - PTY
    13h 5m
    $262–854

  3. Bus

    1. Take the bus from San Francisco to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles to Managuabus bus
    3. Take the bus from Managua to Terminal NicaBusbus bus
    4. Take the bus from Terminal Tica Bus to Terminal Albrookbus bus
    5d 17h
    $495–648

  4. Drive 6,676 km

    1. Drive from San Francisco to Panama Citycar car 6,676 km
    3d 11h
    $914–1,320

  5. Fly San Francisco International Airport to David

    1. Fly from San Francisco International Airport (SFO) to David (DAV)plane plane SFO - DAV
    11h 56m
    $303–1,116

  6. Fly Oakland International Airport to Tocumen International Airport

    1. Fly from Oakland International Airport (OAK) to Tocumen International Airport (PTY)plane plane OAK - PTY
    12h 11m
    $396–798

San Francisco International Airport (SFO) to Tocumen International Airport (PTY) flights

Calendar32Weekly Planes
Duration8h 59mAverage Duration
Ticket$191Cheapest Price
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Questions & Answers

Map of how to get from San Francisco to Panama.ExpandLaunch map view
  • Distance: 5,389.8 km
  • Duration: 10h 26m

What companies run services between San Francisco, CA, USA and Panama?

Copa Airlines, Avianca - Aerovías del Continente Americano S.A., and Aeroméxico fly from San Francisco International Airport (SFO) to Tocumen International Airport (PTY) 5 times a day. Alternatively, you can take a bus from San Francisco to Fernandez de Cordoba via Los Angeles Union Station, Cesar E Chavez / Vignes, Los Angeles, Managua, Terminal NicaBus, Terminal Tica Bus, Terminal Albrook, and Albrook in around 5d 17h.

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Want to know more about travelling around Panama

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