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How to get fromSan Francisco to Saint Charlesby plane, bus (Flixbus, Greyhound), train, shuttle, car, or train (Amtrak)

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There are 8 ways to get from San Francisco to Saint Charles by plane, bus (Flixbus, Greyhound), train, shuttle, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from San Francisco International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to Lambert–St. Louis International Airport (STL)plane plane SFO - STL
    6h 24m
    $144–446

  2. Bus

    1. Take the bus from San Francisco to Los Angeles Union Stationbus bus FlixBus 2005
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus Greyhound US1210
    2d 3h
    $352–666

  3. Train, shuttle

    1. Take the train from Richmond to Galesburg Amtrak Stationtrain train
    2. Take the train from Galesburg Amtrak Station to Quincy Amtrak Stationtrain train
    3. Take a shuttle bus from Hannibal to St. Louisshuttle bus
    2d 9h
    $815–1,684

  4. Drive 2,028.6 mi

    1. Drive from San Francisco to Saint Charlescar car 2,028.6 mi
    31h 30m
    $371–535

  5. Fly from Oakland International Airport

    1. Fly from Oakland International Airport (OAK) to Lambert–St. Louis International Airport (STL)plane plane OAK - STL
    8h 8m
    $210–862

  6. Caltrain to Norman Y. Mineta San José International Airport, fly

    1. Take the train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Lambert–St. Louis International Airport (STL)plane plane SJC - STL
    9h 13m
    $206–818

  7. Train to Sacramento International Airport, fly

    1. Take the train from Richmond to Sacramentotrain train
    2. Fly from Sacramento International Airport (SMF) to Lambert–St. Louis International Airport (STL)plane plane SMF - STL
    9h 44m
    $245–769

  8. Train (Amtrak)

    1. Take the train from Oakland to Los Angelestrain train Coast Starlight
    2. Take the train from Los Angeles to St. Louistrain train Texas Eagle
    2d 23h
    $907–1,918

San Francisco to Saint Charles by bus and train

Calendar4Weekly Services
Duration2d 3hAverage Duration
Ticket$352Cheapest Price
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Questions & Answers

Map of how to get from San Francisco to Saint Charles.ExpandLaunch map view
  • Distance: 1,760.1 mi
  • Duration: 6h 24m

What companies run services between San Francisco, CA, USA and Saint Charles, MO, USA?

United Airlines, Southwest Airlines, and Delta fly from San Francisco International Airport (SFO) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from San Francisco to 4375 Rider Trail North Sb via Los Angeles Union Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, and North Hanley Transit Center in around 2d 3h.

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