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How to get fromSan Francisco to St. Louisby plane, bus (Flixbus, Greyhound), train, bus, or car

Find Transport to St. Louis

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There are 7 ways to get from San Francisco to St. Louis by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from San Francisco International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to Lambert–St. Louis International Airport (STL)plane plane SFO - STL
    6h
    $143–405

  2. Bus

    1. Take the bus from San Francisco to Los Angeles Union Stationbus bus FlixBus 2005
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus Greyhound US1210
    2d 1h
    $370–713

  3. Train, bus (Amtrak)

    1. Take the train from Richmond to Galesburg Amtrak Stationtrain train
    2. Take the bus from Galesburg Amtrak Station to Springfieldbus bus
    3. Take the train from Springfield to St. Louistrain train
    2d 8h
    $775–1,631

  4. Drive 2,048.4 mi

    1. Drive from San Francisco to St. Louiscar car 2,048.4 mi
    31h 50m
    $374–540

  5. Fly from Oakland International Airport

    1. Fly from Oakland International Airport (OAK) to Lambert–St. Louis International Airport (STL)plane plane OAK - STL
    7h 44m
    $219–911

  6. Caltrain to Norman Y. Mineta San José International Airport, fly

    1. Take the train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Lambert–St. Louis International Airport (STL)plane plane SJC - STL
    8h 48m
    $215–867

  7. Train to Sacramento International Airport, fly

    1. Take the train from Richmond to Sacramentotrain train
    2. Fly from Sacramento International Airport (SMF) to Lambert–St. Louis International Airport (STL)plane plane SMF - STL
    9h 17m
    $256–817

San Francisco to St. Louis by bus

Calendar10Weekly Buses
Duration2d 1hAverage Duration
Ticket$370Cheapest Price
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Questions & Answers

Map of how to get from San Francisco to St. Louis.ExpandLaunch map view
  • Distance: 1,760 mi
  • Duration: 6h

What companies run services between San Francisco, CA, USA and St. Louis, MO, USA?

United Airlines, Southwest Airlines, and Delta fly from San Francisco International Airport (SFO) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from San Francisco to St Louis Bus Station via Los Angeles Union Station in around 2d 1h.

Airlines
Train operators
Bus operators

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