Rome2Rio

How to get fromSan Francisco to Winston-Salemby plane, bus (Flixbus, Greyhound), train, bus, car, or train (Amtrak)

Find Transport to Winston-Salem

See all options

There are 9 ways to get from San Francisco to Winston-Salem by plane, bus (Flixbus, Greyhound), train, bus, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Francisco International Airport to Piedmont Triad International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to Piedmont Triad International Airport (GSO)plane plane SFO - GSO
    9h 25m
    $279–1,035

  2. Fly San Francisco International Airport to Raleigh-Durham International Airport, bus

    cheapest
    1. Fly from San Francisco International Airport (SFO) to Raleigh-Durham International Airport (RDU)plane plane SFO - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    10h 49m
    $208–441

  3. Bus

    1. Take the bus from San Francisco to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    2d 17h
    $443–867

  4. Train, bus

    1. Take the train from Richmond to Chicago Union Stationtrain train
    2. Take the bus from Chicago to Columbus - Mound Stbus bus
    3. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    3d 1h
    $845–1,806

  5. Drive 2,702.1 mi

    1. Drive from San Francisco to Winston-Salemcar car 2,702.1 mi
    44h 9m
    $494–713

  6. Caltrain to Norman Y. Mineta San José International Airport, fly to Piedmont Triad International Airport

    1. Take the train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Piedmont Triad International Airport (GSO)plane plane SJC - GSO
    10h 54m
    $321–1,237

  7. Fly San Francisco International Airport to Charlotte Douglas International Airport, bus

    1. Fly from San Francisco International Airport (SFO) to Charlotte Douglas International Airport (CLT)plane plane SFO - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    9h 45m
    $241–958

  8. Fly Oakland International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Oakland International Airport (OAK) to Charlotte Douglas International Airport (CLT)plane plane OAK - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    11h 24m
    $287–1,154

  9. Train (Amtrak)

    1. Take the train from Richmond to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to High Pointtrain train
    3d 11h
    $1,125–2,421

San Francisco to Winston-Salem by bus

Calendar4Weekly Buses
Duration2d 17hAverage Duration
Ticket$443Cheapest Price
See schedules

Questions & Answers

Map of how to get from San Francisco to Winston-Salem.ExpandLaunch map view
  • Distance: 2,366 mi
  • Duration: 9h 25m

What companies run services between San Francisco, CA, USA and Winston-Salem, NC, USA?

Delta, American Airlines, and United Airlines fly from San Francisco International Airport (SFO) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from San Francisco to Winston Salem(Trans Center) via Los Angeles Union Station, Dallas Bus Station, and Atlanta Bus Station in around 2d 17h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers