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How to get fromSan Jose to Otay Mesaby plane, tram, bus, train (Amtrak), car, subway, train, or bus (Greyhound)

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There are 7 ways to get from San Jose to Otay Mesa by plane, tram, bus, train (Amtrak), car, subway, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Norman Y. Mineta San José International Airport, tram

    best
    1. Fly from Norman Y. Mineta San José International Airport (SJC) to San Diego International Airport (SAN)plane plane SJC - SAN
    2. Take the tram from Civic Center Station to Iris Avenue Stationtram tram
    4h 8m
    $78–526

  2. Bus

    1. Take the bus from San Jose - King Rd to San Ysidrobus bus San Jose
    10h 36m
    $96–123

  3. Train (Amtrak)

    1. Take the train from San Jose to Los Angelestrain train Coast Starlight
    2. Take the train from Los Angeles to San Diego Old Town Transportation Centertrain train Pacific Surfliner
    15h 46m
    $174–380

  4. Drive 474.3 mi

    1. Drive from San Jose to Otay Mesacar car 474.3 mi
    8h 8m
    $87–125

  5. BART to Oakland International Airport, fly

    1. Take the subway from Berryessa / North San Jose to Coliseumsubway subway
    2. Fly from Oakland International Airport (OAK) to San Diego International Airport (SAN)plane plane OAK - SAN
    5h 4m
    $90–296

  6. Caltrain to San Francisco International Airport, fly

    1. Take the train from San Jose Diridon Caltrain Northbound to Millbrae Caltrain Northboundtrain train
    2. Fly from San Francisco International Airport (SFO) to San Diego International Airport (SAN)plane plane SFO - SAN
    5h 19m
    $82–274

  7. Bus via San Jose Diridon Station (Greyhound)

    1. Take the bus from San Jose Diridon Station to San Ysidro Bus Terminalbus bus Greyhound US0831
    12h 37m
    $79–151

San Jose to Otay Mesa by bus and tram

Calendar14Weekly Services
Duration10h 36mAverage Duration
Ticket$96Cheapest Price
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Questions & Answers

Map of how to get from San Jose to Otay Mesa.ExpandLaunch map view
  • Distance: 442.1 mi
  • Duration: 4h 8m

What companies run services between San Jose, CA, USA and Otay Mesa, CA, USA?

Tufesa operates a bus from San Jose - King Rd to San Ysidro twice daily. Tickets cost $90–120 and the journey takes 10h. Alternatively, you can take a train from San Jose to Otay Mesa Rd & Cactus Rd via Los Angeles, San Diego Old Town Transportation Center, Old Town Station, Iris Avenue Station, and Iris Avenue Transit Center in around 15h 46m.

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