There are 4 ways to get from San Juan to La Serena by plane, car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Isla Grande Airport to La Florida Airport
best- Fly from Isla Grande Airport (SIG) to La Florida Airport (LSC)plane SIG - LSC
18h 37m$290–950Drive to Eugenio María De Hostos Airport, fly to La Florida Airport
cheapest- Drive from San Juan to Eugenio María De Hostos Airport (MAZ)car
- Fly from Eugenio María De Hostos Airport (MAZ) to La Florida Airport (LSC)plane MAZ - LSC
18h 13m$207–725Fly Luis Munoz Marin International Airport to La Florida Airport
- Fly from Luis Munoz Marin International Airport (SJU) to La Florida Airport (LSC)plane SJU - LSC
16h 31m$245–775Fly Luis Munoz Marin International Airport to Comodoro Arturo Merino Benítez International Airport, bus
- Fly from Luis Munoz Marin International Airport (SJU) to Comodoro Arturo Merino Benítez International Airport (SCL)plane SJU - SCL
- Take the bus from Santiago to Terminal de buses La Serenabus
19h 49m$368–814
Isla Grande Airport (SIG) to La Florida Airport (LSC) flights
Questions & Answers
The cheapest way to get from San Juan to La Serena is to drive and fly which costs $200 - $750 and takes 18h 13m.
The fastest way to get from San Juan to La Serena is to fly which takes 16h 31m and costs $240 - $800.
The distance between San Juan and La Serena is 5407 km.
It takes approximately 18h 37m to fly from Isla Grande Airport (SIG) to La Florida Airport (LSC), including transfers and time at the airport.
There is no direct flight from Isla Grande Airport Airport to La Florida Airport Airport. The quickest flight takes 24h 37m and has four stopovers.
World Ticket, Sky Airline, Arajet and five other airlines offer flights from Isla Grande Airport Airport to La Florida Airport Airport.
There are 966+ hotels available in La Serena.
What companies run services between San Juan, Puerto Rico and La Serena, Chile?
Vieques Air Link, Cape Air, and six other airlines fly from Isla Grande Airport (SIG) to La Florida Airport (LSC) once daily.
- Website
- latam.com
Flights from Isla Grande Airport to La Florida Airport via Culebra, Luis Munoz Marin International Airport, Punta Cana, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 25h 11m
- When
- Friday
- Estimated price
- $320–1,100
Flights from Isla Grande Airport to La Florida Airport via Vieques, Luis Munoz Marin International Airport, Punta Cana, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 25h 26m
- When
- Friday and Saturday
- Estimated price
- $290–950
Flights from Isla Grande Airport to La Florida Airport via Vieques, Luis Munoz Marin International Airport, Bogota, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 18h 37m
- When
- Wednesday and Sunday
- Estimated price
- $350–1,100
Flights from Isla Grande Airport to La Florida Airport via Culebra, Luis Munoz Marin International Airport, Bogota, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 25h 7m
- When
- Wednesday and Sunday
- Estimated price
- $350–1,100
Flights from Luis Munoz Marin International Airport to La Florida Airport via Miami, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 14h 11m
- When
- Wednesday and Sunday
- Estimated price
- $320–950
Flights from Luis Munoz Marin International Airport to La Florida Airport via Bogota, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 14h 17m
- When
- Wednesday and Sunday
- Estimated price
- $270–850
Flights from Luis Munoz Marin International Airport to La Florida Airport via Panama City, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 15h 20m
- When
- Wednesday, Sunday, and Friday
- Estimated price
- $190–700
Flights from Luis Munoz Marin International Airport to La Florida Airport via Punta Cana, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 21h 38m
- When
- Friday and Saturday
- Estimated price
- $250–750
Flights from Eugenio María De Hostos Airport to La Florida Airport via Luis Munoz Marin International Airport, Punta Cana, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 25h 21m
- When
- Friday and Saturday
- Estimated price
- $240–750
Flights from Eugenio María De Hostos Airport to La Florida Airport via Luis Munoz Marin International Airport, Bogota, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 16h 16m
- When
- Wednesday and Sunday
- Estimated price
- $260–800
Flights from Eugenio María De Hostos Airport to La Florida Airport via Luis Munoz Marin International Airport, Panama City, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 19h 33m
- When
- Wednesday and Sunday
- Estimated price
- $190–700
Flights from Luis Munoz Marin International Airport to Comodoro Arturo Merino Benítez International Airport via Punta Cana
- Ave. Duration
- 9h 57m
- When
- Friday and Saturday
- Estimated price
- $240–750
- Website
- jetsmart.com
Flights from Luis Munoz Marin International Airport to La Florida Airport via Medellin Jose Marie Cordova, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 25h
- When
- Thursday
- Estimated price
- $260–700
Flights from Eugenio María De Hostos Airport to La Florida Airport via Luis Munoz Marin International Airport, Medellin Jose Marie Cordova, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 29h
- When
- Thursday
- Estimated price
- $250–700
Flights from Luis Munoz Marin International Airport to Comodoro Arturo Merino Benítez International Airport via Medellin Jose Marie Cordova
- Ave. Duration
- 12h 36m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $240–700
- Website
- skyairline.com
Flights from Isla Grande Airport to La Florida Airport via Vieques, Luis Munoz Marin International Airport, Bogota, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 28h 16m
- When
- Saturday
- Estimated price
- $350–1,100
Flights from Luis Munoz Marin International Airport to La Florida Airport via Santo Domingo, Lima, Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 22h 30m
- When
- Sunday
- Estimated price
- $320–900
- Website
- avianca.com
Flights from Luis Munoz Marin International Airport to Comodoro Arturo Merino Benítez International Airport via Bogota
- Ave. Duration
- 10h 12m
- When
- Every day
- Estimated price
- $260–850
- Website
- copaair.com
Flights from Luis Munoz Marin International Airport to Comodoro Arturo Merino Benítez International Airport via Panama City
- Ave. Duration
- 12h 29m
- When
- Every day
- Estimated price
- $190–700
- Website
- Flixbus Chile
Bus from Santiago to Terminal de buses La Serena
- Ave. Duration
- 5h 35m
- Frequency
- Every 2 hours
- Estimated price
- $50–85
- Schedules at
- Flixbus Chile
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