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How to get fromSan Luis Obispo to Buffaloby plane, bus, train, bus (Flixbus, Greyhound), car, shuttle, or train (Amtrak)

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There are 8 ways to get from San Luis Obispo to Buffalo by plane, bus, train, bus (Flixbus, Greyhound), car, shuttle, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Luis Obispo County Regional Airport to Buffalo Niagara International Airport

    best
    1. Fly from San Luis Obispo County Regional Airport (SBP) to Buffalo Niagara International Airport (BUF)plane plane SBP - BUF
    8h 59m
    $202–830
  2. Bus, train

    1. Take the bus from San Luis Obispo Railroad Museum to Los Angeles Union Stationbus bus
    2. Take the train from Los Angeles to Chicago Union Stationtrain train
    3. Take the bus from Chicago to Clevelandbus bus
    4. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    2d 12h
    $779–1,690
  3. Bus

    1. Take the bus from San Luis Obispo Railroad Museum to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Columbusbus bus
    4. Take the bus from Columbus - Mound St to Buffalo, NYbus bus
    2d 16h
    $421–810
  4. Drive 2,665.3 mi

    1. Drive from San Luis Obispo to Buffalocar car 2,665.3 mi
    43h 5m
    $487–703
  5. Bus to Santa Barbara Municipal Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from San Luis Obispo to Uc Santa Barbara Amtrak Bus Stopbus bus
    2. Fly from Santa Barbara Municipal Airport (SBA) to Buffalo Niagara International Airport (BUF)plane plane SBA - BUF
    10h 55m
    $228–880
  6. Fly San Luis Obispo County Regional Airport to Toronto Pearson International Airport, shuttle

    1. Fly from San Luis Obispo County Regional Airport (SBP) to Toronto Pearson International Airport (YYZ)plane plane SBP - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    12h 52m
    $202–610
  7. Train to Los Angeles International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from San Luis Obispo to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Buffalo Niagara International Airport (BUF)plane plane LAX - BUF
    13h 25m
    $321–1,188
  8. Train (Amtrak)

    1. Take the train from San Luis Obispo to Los Angelestrain train
    2. Take the train from Los Angeles to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    2d 14h
    $944–2,136

San Luis Obispo to Buffalo by bus, foot, and train

Calendar4Weekly Services
Duration2d 12hAverage Duration
Ticket$779Cheapest Price
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Questions & Answers

What companies run services between San Luis Obispo, CA, USA and Buffalo, NY, USA?

United Airlines, American Airlines, and two other airlines fly from San Luis Obispo County Regional Airport (SBP) to Buffalo Niagara International Airport (BUF) 3 times a day. Alternatively, you can take a bus from San Luis Obispo Railroad Museum to Buffalo, NY via Los Angeles Union Station, St Louis Bus Station, and Columbus - Mound St in around 2d 16h.

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