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How to get fromSan Luis Obispo to Hesperiaby bus (Flixbus), train, bus, car, plane, or train (Amtrak)

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There are 7 ways to get from San Luis Obispo to Hesperia by bus (Flixbus), train, bus, car, plane, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from San Luis Obispo Railroad Museum to Los Angeles Union Stationbus bus FlixBus 2005
    2. Take the bus from Downtown Los Angeles to Hesperia, CAbus bus San Ysidro
    7h 59m
    $62–115

  2. Drive 245.6 mi

    cheapest
    1. Drive from San Luis Obispo to Hesperiacar car 245.6 mi
    4h 48m
    $45–65

  3. Train, bus

    1. Take the train from San Luis Obispo to Los Angelestrain train Pacific Surfliner / ...
    2. Take the bus from Downtown Los Angeles to Hesperia, CAbus bus San Ysidro
    9h 22m
    $103–209

  4. Fly to Los Angeles International Airport, bus

    1. Fly from San Luis Obispo County Regional Airport (SBP) to Los Angeles International Airport (LAX)plane plane SBP - LAX
    2. Take the bus from Downtown Los Angeles to Hesperia, CAbus bus
    7h 11m
    $260–518

  5. Train (Amtrak)

    1. Take the train from San Luis Obispo to Los Angelestrain train Pacific Surfliner / ...
    2. Take the train from Los Angeles to Victorville Amtraktrain train Southwest Chief
    9h 41m
    $135–255

  6. Train, bus via El Monte

    1. Take the train from San Luis Obispo to Los Angelestrain train Pacific Surfliner / ...
    2. Take the bus from El Monte Bus Stop to Victorville Transit Centerbus bus Greyhound US0900
    12h 8m
    $85–179

  7. Fly to Ontario International Airport, bus

    1. Fly from San Luis Obispo County Regional Airport (SBP) to Ontario International Airport (ONT)plane plane SBP - ONT
    2. Take the bus from 285 S East End Ave - Pomona to Hesperia, CAbus bus
    9h 28m
    $78–326

San Luis Obispo to Hesperia by bus and foot

Calendar4Weekly Services
Duration7h 59mAverage Duration
Ticket$62Cheapest Price
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Questions & Answers

Map of how to get from San Luis Obispo to Hesperia.ExpandLaunch map view
  • Distance: 277.9 mi
  • Duration: 7h 59m

What companies run services between San Luis Obispo, CA, USA and Hesperia, CA, USA?

You can take a bus from San Luis Obispo Railroad Museum to Main St EB & 3rd Ave via Patsaouras Transit Plaza at Union Station, Spring St & 7th St, Downtown Los Angeles, Hesperia, CA, and Main St EB & Escondido Ave NS in around 7h 59m. Alternatively, you can take a train from San Luis Obispo to Hesperia via Los Angeles and Victorville Amtrak in around 9h 41m.

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