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How to get fromSan Luis Obispo to Louisvilleby plane, bus (Flixbus, Greyhound), train, bus, or car

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There are 8 ways to get from San Luis Obispo to Louisville by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Luis Obispo County Regional Airport to Louisville International Airport

    best
    1. Fly from San Luis Obispo County Regional Airport (SBP) to Louisville International Airport (SDF)plane plane SBP - SDF
    9h 2m
    $172–704

  2. Bus

    1. Take the bus from San Luis Obispo Railroad Museum to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Louisville, KYbus bus
    2d 5h
    $370–704

  3. Train, bus via Chicago (Amtrak)

    1. Take the train from San Luis Obispo to Fullerton Amtrak Stationtrain train
    2. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    2d 11h
    $860–1,837

  4. Drive 2,203.4 mi

    1. Drive from San Luis Obispo to Louisvillecar car 2,203.4 mi
    35h 46m
    $403–581

  5. Fly San Luis Obispo County Regional Airport to Blue Grass Airport, drive

    1. Fly from San Luis Obispo County Regional Airport (SBP) to Blue Grass Airport (LEX)plane plane SBP - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    9h 24m
    $264–1,120

  6. Bus to Santa Barbara Municipal Airport, fly to Louisville International Airport

    1. Take the bus from San Luis Obispo to Uc Santa Barbara Amtrak Bus Stopbus bus
    2. Fly from Santa Barbara Municipal Airport (SBA) to Louisville International Airport (SDF)plane plane SBA - SDF
    10h 42m
    $197–754

  7. Fly San Luis Obispo County Regional Airport to Covington, bus

    1. Fly from San Luis Obispo County Regional Airport (SBP) to Covington (CVG)plane plane SBP - CVG
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    11h 36m
    $192–798

  8. Train, bus

    1. Take the train from San Luis Obispo to Los Angelestrain train
    2. Take the train from Los Angeles to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Louisville, KYbus bus
    2d 21h
    $881–1,851

San Luis Obispo to Louisville by bus

Calendar7Weekly Buses
Duration2d 5hAverage Duration
Ticket$370Cheapest Price
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Questions & Answers

Map of how to get from San Luis Obispo to Louisville.ExpandLaunch map view
  • Distance: 1,943.8 mi
  • Duration: 9h 2m

What companies run services between San Luis Obispo, CA, USA and Louisville, KY, USA?

United Airlines, American Airlines, and three other airlines fly from San Luis Obispo County Regional Airport (SBP) to Louisville International Airport (SDF) 4 times a day. Alternatively, you can take a bus from San Luis Obispo Railroad Museum to Louisville, KY via Los Angeles Union Station, St Louis Bus Station, and Evansville, IN in around 2d 5h.

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