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How to get fromSan Luis Obispo to Mexicaliby bus (Flixbus), train, bus, car, or plane

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There are 9 ways to get from San Luis Obispo to Mexicali by bus (Flixbus), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Flixbus)

    best
    1. Take the bus from San Luis Obispo Railroad Museum to Los Angeles Union Stationbus bus FlixBus 2005
    2. Take the bus from Los Angeles Downtown to Calexico Bus Stationbus bus FlixBus 2054
    11h 24m
    $1,123–1,950

  2. Fly San Luis Obispo County Regional Airport to Yuma International Airport, bus

    cheapest
    1. Fly from San Luis Obispo County Regional Airport (SBP) to Yuma International Airport (YUM)plane plane SBP - YUM
    2. Take the bus from San Luis Río Colorado to Mexicalibus bus
    9h 9m
    $1,038–5,846

  3. Train, bus

    1. Take the train from San Luis Obispo to San Diegotrain train Pacific Surfliner
    2. Take the bus from Tijuana to Mexicalibus bus
    13h 2m
    $2,300–4,806

  4. Drive 662.6 km

    1. Drive from San Luis Obispo to Mexicalicar car 662.6 km
    7h 22m
    $1,283–1,853

  5. Fly San Luis Obispo County Regional Airport to San Diego International Airport, bus

    1. Fly from San Luis Obispo County Regional Airport (SBP) to San Diego International Airport (SAN)plane plane SBP - SAN
    2. Take the bus from Tijuana to Mexicalibus bus
    7h 24m
    $3,349–7,026

  6. Train, bus via Los Angeles

    1. Take the train from San Luis Obispo to Los Angelestrain train Pacific Surfliner / ...
    2. Take the bus from El Monte Bus Stop to Calexico Bus Stationbus bus Greyhound US0850
    14h 45m
    $1,802–3,626

  7. Train to Los Angeles International Airport, fly to Imperial County Airport

    1. Take the train from San Luis Obispo to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Imperial County Airport (IPL)plane plane LAX - IPL
    9h 31m
    $2,799–10,293

  8. Fly San Luis Obispo County Regional Airport to Imperial County Airport

    1. Fly from San Luis Obispo County Regional Airport (SBP) to Imperial County Airport (IPL)plane plane SBP - IPL
    7h 36m
    $1,069–5,621

  9. Bus to Santa Barbara Municipal Airport, fly to San Diego International Airport, bus

    1. Take the bus from San Luis Obispo to Uc Santa Barbara Amtrak Bus Stopbus bus
    2. Fly from Santa Barbara Municipal Airport (SBA) to San Diego International Airport (SAN)plane plane SBA - SAN
    3. Take the bus from Tijuana to Mexicalibus bus
    9h 18m
    $3,741–5,559

San Luis Obispo County Regional Airport (SBP) to San Diego International Airport (SAN) flights

Calendar20Weekly Planes
Duration2h 24mAverage Duration
Ticket$620Cheapest Price
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Questions & Answers

Map of how to get from San Luis Obispo to Mexicali.ExpandLaunch map view
  • Distance: 665.5 km
  • Duration: 11h 24m

What companies run services between San Luis Obispo, CA, USA and Mexicali, Mexico?

You can take a bus from San Luis Obispo Railroad Museum to Central de Autobuses de Mexicali via Los Angeles Union Station, Los Angeles Downtown, Calexico Bus Station, and C. José Azueta y Blvr. López Mateos in around 11h 24m. Alternatively, United Airlines, Southern Airways Express, and American Airlines fly from San Luis Obispo County Regional Airport (SBP) to Imperial County Airport (IPL) 4 times a day.

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