There are 5 ways to get from San Luis Obispo to San Diego by plane, bus (Flixbus, Amtrak), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from San Luis Obispo County Regional Airport
best- Fly from San Luis Obispo County Regional Airport (SBP) to San Diego International Airport (SAN)plane SBP - SAN
2h 42m$170–352Drive 305.6 mi
cheapest- Drive from San Luis Obispo to San Diegocar 305.6 mi
5h 33m$56–81Bus
- Take the bus from San Luis Obispo Railroad Museum to Los Angeles Union Stationbus FlixBus 2005
- Take the bus from Los Angeles to San Diegobus Amtrak Thruway Connecting Service
8h 20m$68–106Train (Amtrak)
- Take the train from San Luis Obispo to San Diegotrain Pacific Surfliner
8h 55m$100–230Bus to Santa Barbara Municipal Airport, fly
- Take the bus from San Luis Obispo to Uc Santa Barbara Amtrak Bus Stopbus
- Fly from Santa Barbara Municipal Airport (SBA) to San Diego International Airport (SAN)plane SBA - SAN
4h 35m$111–270
San Luis Obispo to San Diego by bus and foot
Questions & Answers
The cheapest way to get from San Luis Obispo to San Diego is to drive which costs $55 - $85 and takes 5h 33m.
The fastest way to get from San Luis Obispo to San Diego is to fly which takes 2h 42m and costs $170 - $360.
No, there is no direct bus from San Luis Obispo to San Diego. However, there are services departing from San Luis Obispo Railroad Museum and arriving at San Diego via Los Angeles. The journey, including transfers, takes approximately 8h 20m.
Yes, there is a direct train departing from San Luis Obispo and arriving at San Diego. Services depart three times a day, and operate every day. The journey takes approximately 8h 55m.
The distance between San Luis Obispo and San Diego is 270 miles. The road distance is 307.3 miles.
The best way to get from San Luis Obispo to San Diego without a car is to bus which takes 8h 20m and costs $65 - $110.
It takes approximately 2h 42m to get from San Luis Obispo to San Diego, including transfers.
San Luis Obispo to San Diego bus services, operated by Flixbus USA, depart from San Luis Obispo Railroad Museum station.
San Luis Obispo to San Diego train services, operated by Amtrak, depart from San Luis Obispo station.
The best way to get from San Luis Obispo to San Diego is to fly which takes 2h 42m and costs $170 - $360. Alternatively, you can bus, which costs $65 - $110 and takes 8h 20m, you could also train, which costs $100 - $230 and takes 8h 55m.
What companies run services between San Luis Obispo, CA, USA and San Diego, CA, USA?
Alaska Airlines, Inc. and United Airlines fly from San Luis Obispo County Regional Airport (SBP) to San Diego International Airport (SAN) 3 times a day. Alternatively, you can take a bus from San Luis Obispo Railroad Museum to San Diego via Los Angeles Union Station and Los Angeles in around 8h 20m.
- Website
- alaskaair.com
Flights from San Luis Obispo County Regional Airport to San Diego International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $170–350
Flights from Santa Barbara Municipal Airport to San Diego International Airport
- Ave. Duration
- 1h 4m
- When
- Every day
- Estimated price
- $75–220
- Website
- southwest.com
Flights from Santa Barbara Municipal Airport to San Diego International Airport
- Ave. Duration
- 53 min
- When
- Every day
- Estimated price
- $29–210
- Website
- united.com
Flights from San Luis Obispo County Regional Airport to San Diego International Airport via Los Angeles
- Ave. Duration
- 3h 28m
- When
- Saturday, Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $35–240
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Luis Obispo to San Diego
- Ave. Duration
- 8h 55m
- Frequency
- 3 times a day
- Estimated price
- $100–230
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from San Luis Obispo Railroad Museum to Los Angeles Union Station
- Ave. Duration
- 4h 15m
- Frequency
- 4 times a week
- Estimated price
- $28–50
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Los Angeles to San Diego
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- Amtrak
Bus from San Luis Obispo to Uc Santa Barbara Amtrak Bus Stop
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- $30–50
- Website
- Amtrak
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More Questions & Answers
San Luis Obispo to San Diego bus services, operated by Flixbus USA, arrive at Los Angeles Union Station.
San Luis Obispo to San Diego train services, operated by Amtrak, arrive at San Diego station.
Yes, the driving distance between San Luis Obispo to San Diego is 307 miles. It takes approximately 5h 33m to drive from San Luis Obispo to San Diego.
Book your San Luis Obispo to San Diego train tickets online with Omio.
Book your San Luis Obispo to San Diego bus tickets online with Omio.
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