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How to get fromSan Luis Obispo to San Ysidroby plane, tram, bus (Flixbus, Greyhound), train (Amtrak), car, or bus

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There are 6 ways to get from San Luis Obispo to San Ysidro by plane, tram, bus (Flixbus, Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from San Luis Obispo County Regional Airport, tram

    best
    1. Fly from San Luis Obispo County Regional Airport (SBP) to San Diego International Airport (SAN)plane plane SBP - SAN
    2. Take the tram from City College Station to Beyer Blvd Stationtram tram
    4h 28m
    $174–372

  2. Bus

    cheapest
    1. Take the bus from San Luis Obispo Railroad Museum to Los Angeles Union Stationbus bus FlixBus 2005
    2. Take the bus from Los Angeles Union Station to San Ysidrobus bus Los Angeles
    8h 45m
    $56–94

  3. Train (Amtrak)

    1. Take the train from San Luis Obispo to San Diegotrain train Pacific Surfliner
    9h 42m
    $113–244

  4. Drive 318.6 mi

    1. Drive from San Luis Obispo to San Ysidrocar car 318.6 mi
    5h 46m
    $59–84

  5. Bus to Santa Barbara Municipal Airport, fly

    1. Take the bus from San Luis Obispo to Uc Santa Barbara Amtrak Bus Stopbus bus
    2. Fly from Santa Barbara Municipal Airport (SBA) to San Diego International Airport (SAN)plane plane SBA - SAN
    6h 22m
    $200–291

  6. Bus via Santa Maria Airport (SMX)

    1. Take the bus from Government Center to Santa Maria Transit Centerbus bus 10S
    2. Take the bus from Santa Maria Airport, CA to Los Angeles Airport, CAbus bus
    3. Take the bus from LAX Terminal 3 Shared Rides Stop to San Diegobus bus
    11h 13m
    $146–228

San Luis Obispo to San Ysidro by bus

Calendar8Weekly Buses
Duration8h 45mAverage Duration
Ticket$56Cheapest Price
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Questions & Answers

Map of how to get from San Luis Obispo to San Ysidro.ExpandLaunch map view
  • Distance: 285.4 mi
  • Duration: 4h 28m

What companies run services between San Luis Obispo, CA, USA and San Ysidro, CA, USA?

You can take a bus from San Luis Obispo Railroad Museum to San Ysidro via Los Angeles Union Station in around 8h 45m. Alternatively, Amtrak operates a train from San Luis Obispo to San Diego 3 times a day. Tickets cost $110–230 and the journey takes 8h 55m.

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