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How to get fromSan Mateo to Irvineby plane, train, bus, train (Amtrak), car, tram, or subway

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There are 7 ways to get from San Mateo to Irvine by plane, train, bus, train (Amtrak), car, tram, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from San Francisco International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to John Wayne Airport Orange County (SNA)plane plane SFO - SNA
    2h 56m
    $122–715

  2. Caltrain, bus

    cheapest
    1. Take the train from San Mateo Caltrain Southbound to San Jose Diridon Caltrain Southboundtrain train Local Weekday / ...
    2. Take the bus from San Jose Diridon Station to Anaheim Regional Transportation Intermodal Centerbus bus Greyhound US0831
    12h 4m
    $64–121

  3. Caltrain, bus, train

    1. Take the train from San Mateo Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Take the bus from San Jose, CA - Huong Lan Sandwich to Los Angeles, CA - Chinatown Stationbus bus
    3. Take the train from L.A. Union Station to Tustintrain train
    10h 21m
    $65–85

  4. Caltrain, train

    1. Take the train from San Mateo Caltrain Southbound to San Jose Diridon Caltrain Southboundtrain train
    2. Take the train from San Jose to Los Angelestrain train
    3. Take the train from L.A. Union Station to Tustintrain train
    14h 39m
    $145–301

  5. Drive 407.9 mi

    1. Drive from San Mateo to Irvinecar car 407.9 mi
    6h 55m
    $75–108

  6. Caltrain to Norman Y. Mineta San José International Airport, fly

    1. Take the train from San Mateo Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to John Wayne Airport Orange County (SNA)plane plane SJC - SNA
    3h 27m
    $200–811

  7. Caltrain, tram, BART to Oakland International Airport, fly

    1. Take the train from San Mateo Caltrain Northbound to San Francisco Caltrain Northboundtrain train
    2. Take the tram from King St & 4th St to Metro Embarcadero Stationtram tram
    3. Take the subway from Embarcadero to Coliseumsubway subway
    4. Fly from Oakland International Airport (OAK) to John Wayne Airport Orange County (SNA)plane plane OAK - SNA
    3h 55m
    $223–767

San Mateo to Irvine by train, bus, and tram

Calendar7Weekly Services
Duration10h 21mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

Map of how to get from San Mateo to Irvine.ExpandLaunch map view
  • Distance: 378.2 mi
  • Duration: 2h 56m

What companies run services between San Mateo, CA, USA and Irvine, CA, USA?

Frontier Airlines, Alaska Airlines, Inc., and two other airlines fly from San Francisco International Airport (SFO) to John Wayne Airport Orange County (SNA) hourly. Alternatively, you can take a train from San Mateo Caltrain Southbound to Tustin via San Jose Diridon Caltrain Southbound, San Jose, Los Angeles, and L.A. Union Station in around 14h 39m.

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