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How to get fromSan Sebastián de los Reyes to Florenceby plane, train (Renfe, Ouigo, Trenitalia), bus, car, train, or train (Renfe, TGV, Trenitalia)

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There are 8 ways to get from San Sebastián de los Reyes to Florence by plane, train (Renfe, Ouigo, Trenitalia), bus, car, train, or train (Renfe, TGV, Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport

    best
    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Florence Peretola Airport (FLR)plane plane MAD - FLR
    4h 52m
    €64–154

  2. Train via Barcelona

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    2. Take the train from Barcelona-Sants to Lyon Part Dieutrain train
    3. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    18h 6m
    €222–486

  3. Bus

    1. Take the bus from Madrid to Genoabus bus FlixBus N1138
    2. Take the bus from Genoa to Florence Villa Constanza Bus Stationbus bus 510 / ...
    26h 50m
    €144–252

  4. Drive 1,633 km

    1. Drive from San Sebastián de los Reyes to Florencecar car 1,633 km
    16h 14m
    €256–369

  5. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Bologna Guglielmo Marconi Airport (BLQ)plane plane MAD - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    5h 23m
    €71–199

  6. Fly to Pisa International Airport, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Pisa International Airport (PSA)plane plane MAD - PSA
    2. Take the train from Pisa Centrale to Firenze S.M.N.train train
    6h 6m
    €71–205

  7. Train

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain train
    2. Take the train from Marseille-Saint-Charles to Nice-Villetrain train
    3. Take the train from Ventimiglia to Pisa Centraletrain train Ic
    4. Take the train from Pisa Centrale to Firenze S.M.N.train train Re
    21h 22m
    €235–460

  8. Bus via Nice Airport (NCE)

    1. Take the bus from Madrid - Barajas Airport T4 to Nice - Airport Bus Station Terminal 1bus bus
    2. Take the bus from Nice - Airport Bus Station Terminal 1 to Pisa Airportbus bus
    3. Take the bus from Pisa International Airport to Florence Airportbus bus
    30h 28m
    €171–329

San Sebastián de los Reyes to Florence by train

Calendar14Weekly Trains
Duration18h 6mAverage Duration
Ticket€222Cheapest Price
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Questions & Answers

Map of how to get from San Sebastián de los Reyes to Florence.ExpandLaunch map view
  • Distance: 1,287.1 km
  • Duration: 4h 52m

What companies run services between San Sebastián de los Reyes, Spain and Florence, Italy?

Iberia and Vueling Airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Florence Peretola Airport (FLR) 5 times a day. Alternatively, you can take a train from Alcobendas-San Sebastián de los Reyes to Firenze S.M.N. via Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, Lyon Part Dieu, and Milano Centrale in around 18h 6m.

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