There are 7 ways to get from San Sebastián de los Reyes to Rome by plane, train (Renfe, Ouigo, Trenitalia), bus, car, or train (Renfe, TGV, Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Fiumicino International Airport
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Fiumicino International Airport (FCO)plane MAD - FCO
4h 59m€36–139Train via Barcelona
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Roma Terminitrain
19h 13m€262–546Bus
- Take the bus from Madrid to Genoabus FlixBus N1138
- Take the bus from Genoa - Via Fanti d'Italia Bus Stop to Rome Tiburtina Largo Mazzonibus 18
30h 15m€165–292Drive 1,906.8 km
- Drive from San Sebastián de los Reyes to Romecar 1,906.8 km
18h 43m€301–435Fly to Roma Ciampino Airport
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Roma Ciampino Airport (CIA)plane MAD - CIA
8h 43m€74–287Train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the train from Marseille-Saint-Charles to Nice-Villetrain
- Take the train from Ventimiglia to Roma Terminitrain Ic
23h 19m€261–504Bus via Siena
- Take the bus from Madrid - Barajas Airport T4 to Nice - Airport Bus Station Terminal 1bus
- Take the bus from Nice - Airport Bus Station Terminal 1 to Sienabus
- Take the bus from Siena to Roma - Via Vincenzo Giudicebus
36h 57m€189–342
San Sebastián de los Reyes to Rome by train
Questions & Answers
The cheapest way to get from San Sebastián de los Reyes to Rome is to fly which costs €35 - €140 and takes 4h 59m.
The fastest way to get from San Sebastián de los Reyes to Rome is to fly which takes 4h 59m and costs €35 - €140.
No, there is no direct bus from San Sebastián de los Reyes to Rome. However, there are services departing from Pºeuropa-Av.Montes De Oca and arriving at Rome Tiburtina Largo Mazzoni via Avenida De Asturias - Plaza De Castilla, Cibeles - Ayuntamiento, Madrid and Genoa - Via Fanti d'Italia Bus Stop. The journey, including transfers, takes approximately 30h 15m.
No, there is no direct train from San Sebastián de los Reyes to Rome. However, there are services departing from Alcobendas-San Sebastián de los Reyes and arriving at Roma Termini via Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, Lyon Part Dieu and Milano Centrale. The journey, including transfers, takes approximately 19h 13m.
The distance between San Sebastián de los Reyes and Rome is 1375 km. The road distance is 1906.8 km.
The best way to get from San Sebastián de los Reyes to Rome without a car is to train via Barcelona which takes 19h 13m and costs €260 - €550.
It takes approximately 4h 59m to get from San Sebastián de los Reyes to Rome, including transfers.
San Sebastián de los Reyes to Rome bus services, operated by FlixBus, depart from Madrid station.
San Sebastián de los Reyes to Rome train services, operated by Renfe AVE, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
The best way to get from San Sebastián de los Reyes to Rome is to fly which takes 4h 59m and costs €35 - €140. Alternatively, you can train via Barcelona, which costs €260 - €550 and takes 19h 13m, you could also bus, which costs €160 - €300 and takes 30h 15m.
What companies run services between San Sebastián de los Reyes, Spain and Rome, Italy?
Ulendo Airlink, Ryanair, and three other airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Fiumicino International Airport (FCO) hourly. Alternatively, you can take a train from Alcobendas-San Sebastián de los Reyes to Roma Termini via Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, Lyon Part Dieu, and Milano Centrale in around 19h 13m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €45–130
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport via Palma Mallorca
- Ave. Duration
- 4h 10m
- When
- Wednesday
- Estimated price
- €45–130
Flights from Adolfo Suárez Madrid–Barajas Airport to Roma Ciampino Airport via Prague
- Ave. Duration
- 6h 45m
- When
- Monday, Sunday, Saturday, and Tuesday
- Estimated price
- €65–280
Flights from Adolfo Suárez Madrid–Barajas Airport to Roma Ciampino Airport via Cagliari
- Ave. Duration
- 6h 45m
- When
- Saturday and Thursday
- Estimated price
- €55–280
Flights from Adolfo Suárez Madrid–Barajas Airport to Roma Ciampino Airport via Rabat-Salé
- Ave. Duration
- 9h 35m
- When
- Friday
- Estimated price
- €65–280
Flights from Adolfo Suárez Madrid–Barajas Airport to Roma Ciampino Airport via Tirana
- Ave. Duration
- 9h 35m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- €75–200
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- €45–120
- Website
- aireuropa.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 24m
- When
- Every day
- Estimated price
- €45–160
- Website
- ita-airways.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €45–160
- Website
- flyulendo.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- €28–120
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- https://www.renfe.com/es/en
- Phone
- +34 900 926 851
- [email protected]
- Website
- iryo.eu
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- https://iryo.eu/en/home
- Phone
- +34 900 759 781
- Website
- ouigo.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- https://www.ouigo.com/es/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- https://www.renfe.com/es/en
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 6m
- Frequency
- Twice daily
- Estimated price
- €80–130
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 42m
- Frequency
- Twice daily
- Estimated price
- €140–230
- Website
- https://www.renfe.com/es/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- 4 times a day
- Estimated price
- €55–90
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €70–150
- Website
- https://www.italotreno.it/en
- Phone
- +33 4 13 94 30 50
- Website
- zou.maregionsud.fr
Train from Marseille-Saint-Charles to Nice-Ville
- Ave. Duration
- 2h 41m
- Frequency
- Hourly
- Estimated price
- €55–110
- Website
- https://zou.maregionsud.fr/en/
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Marseille-Saint-Charles to Nice-Ville
- Ave. Duration
- 2h 36m
- Frequency
- Every 2 hours
- Estimated price
- €45–75
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Ventimiglia to Roma Termini
- Ave. Duration
- 7h 56m
- Frequency
- 3 times a day
- Estimated price
- €65–140
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Madrid to Genoa
- Ave. Duration
- 21h
- Frequency
- Once daily
- Estimated price
- €130–220
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Genoa - Via Fanti d'Italia Bus Stop to Rome Tiburtina Largo Mazzoni
- Ave. Duration
- 6h 5m
- Frequency
- 4 times a week
- Estimated price
- €30–65
- Website
- https://www.itabus.it/en/home
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Madrid - Barajas Airport T4 to Nice - Airport Bus Station Terminal 1
- Ave. Duration
- 20h 15m
- Frequency
- Once daily
- Estimated price
- €120–230
- Website
- https://www.blablacar.co.uk/bus
Bus from Nice - Airport Bus Station Terminal 1 to Siena
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- €45–85
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +39 0972 24590
- [email protected]
- Website
- autolineemoretti.it
Bus from Siena to Roma - Via Vincenzo Giudice
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a week
- Estimated price
- €20–23
- Schedules at
- autolineemoretti.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Getting to Rome from the airport
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
More Questions & Answers
San Sebastián de los Reyes to Rome bus services, operated by FlixBus, arrive at Genoa station.
San Sebastián de los Reyes to Rome train services, operated by Renfe AVE, arrive at Barcelona-Sants station.
Yes, the driving distance between San Sebastián de los Reyes to Rome is 1907 km. It takes approximately 18h 43m to drive from San Sebastián de los Reyes to Rome.
Book your San Sebastián de los Reyes to Rome train tickets online with Omio.
There are 21731+ hotels available in Rome.








































