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How to get fromSan Sebastián de los Reyes to Sicilyby plane, train, bus, or car ferry

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There are 7 ways to get from San Sebastián de los Reyes to Sicily by plane, train, bus, or car ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Palermo Airport

    best
    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane plane MAD - PMO
    5h 35m
    €55–179

  2. Train, bus

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Gironatrain train Ave
    2. Take the bus from Girona - Bus Station to Nice - Airport Bus Station Terminal 1bus bus
    3. Take the bus from Nice Airport to Napoli P.zza Garibaldibus bus
    4. Take the train from Napoli Centrale to Palermo Centraletrain train Ic
    41h 5m
    €293–588

  3. Train, bus, car ferry

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain train
    2. Take the bus from Marseille to Genoabus bus
    3. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    41h 54m
    €279–458

  4. Fly to Catania–Fontanarossa Airport

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane plane MAD - CTA
    5h 14m
    €56–226

  5. Fly to Trapani Airport

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Trapani Airport (TPS)plane plane MAD - TPS
    8h 7m
    €65–245

  6. Bus via Rome

    1. Take the bus from Madrid, Terminal de autobuses T4 to Marseille, Gare de Marseille-Saint-Charlesbus bus
    2. Take the bus from Marseille, Gare de Marseille-Saint-Charles to Roma, Autostazione Tiburtinabus bus
    3. Take the bus from Roma, Autostazione Tiburtina to Palermo Terminal Busbus bus
    45h 43m
    €213–339

  7. Bus

    1. Take the bus from Madrid to Milanbus bus FlixBus N1138
    2. Take the bus from Milano, Autostazione Lampugnano to Palermobus bus N597
    2d
    €277–469

San Sebastián de los Reyes to Sicily by train and bus

Calendar7Weekly Services
Duration41h 5mAverage Duration
Ticket€293Cheapest Price
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Questions & Answers

Map of how to get from San Sebastián de los Reyes to Sicily.ExpandLaunch map view
  • Distance: 1,497.8 km
  • Duration: 5h 35m

What companies run services between San Sebastián de los Reyes, Spain and Sicily, Italy?

Ryanair, Iberia, and Vueling Airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO) twice daily. Alternatively, you can take a bus from Av.Sierra-C.C.La Viña to Palermo Notarbartolo via Av.Hispanidad-Aeropuerto T4, Madrid, Terminal de autobuses T4, Marseille, Gare de Marseille-Saint-Charles, Roma, Autostazione Tiburtina, Palermo Terminal Bus, and Palermo Centrale in around 45h 43m.

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