There are 9 ways to get from San Sebastián de los Reyes to Siena by plane, train, train (Renfe, Ouigo, Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Florence Peretola Airport (FLR)plane MAD - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 50m€75–173Fly to Pisa International Airport, train
cheapest- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Pisa International Airport (PSA)plane MAD - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
6h 42m€74–222Train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
20h 1m€233–505Bus via Genoa
- Take the bus from Madrid to Genoabus
- Take the bus from Genoa to Florence Villa Constanza Bus Stationbus 510 / ...
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 443 / ...
28h 38m€159–273Drive 1,671.9 km
- Drive from San Sebastián de los Reyes to Sienacar 1,671.9 km
17h 14m€264–382Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Bologna Guglielmo Marconi Airport (BLQ)plane MAD - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
7h 19m€82–228Fly to Fiumicino International Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Fiumicino International Airport (FCO)plane MAD - FCO
- Take the train from Roma Termini to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 43m€75–238Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the train from Marseille-Saint-Charles to Nice-Saint-Augustintrain
- Take the bus from Nice - Airport Bus Station Terminal 1 to Sienabus
22h 54m€244–433Bus
- Take the bus from Méndez Álvaro Estación Sur to Padovabus
- Take the bus from Padova to Florencebus
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
34h 57m€153–202
San Sebastián de los Reyes to Siena by train
Questions & Answers
The cheapest way to get from San Sebastián de los Reyes to Siena is to fly and train which costs €70 - €180 and takes 6h 50m.
The fastest way to get from San Sebastián de los Reyes to Siena is to fly and train which takes 6h 42m and costs €70 - €230.
No, there is no direct bus from San Sebastián de los Reyes to Siena. However, there are services departing from Pºeuropa-Av.Montes De Oca and arriving at Siena via Avenida De Asturias - Plaza De Castilla, Cibeles - Ayuntamiento, Madrid, Genoa and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 28h 38m.
No, there is no direct train from San Sebastián de los Reyes to Siena. However, there are services departing from Alcobendas-San Sebastián de los Reyes and arriving at Siena via Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, Lyon Part Dieu, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 20h 1m.
The distance between San Sebastián de los Reyes and Siena is 1381 km. The road distance is 1671.9 km.
The best way to get from San Sebastián de los Reyes to Siena without a car is to train which takes 20h 1m and costs €230 - €550.
It takes approximately 6h 50m to get from San Sebastián de los Reyes to Siena, including transfers.
San Sebastián de los Reyes to Siena bus services, operated by Tabita Tour, depart from Méndez Álvaro Estación Sur station.
San Sebastián de los Reyes to Siena train services, operated by Renfe AVE, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
The best way to get from San Sebastián de los Reyes to Siena is to train which takes 20h 1m and costs €230 - €550. Alternatively, you can bus via Genoa, which costs €150 - €280 and takes 28h 38m.
What companies run services between San Sebastián de los Reyes, Spain and Siena, Italy?
You can take a train from Alcobendas-San Sebastián de los Reyes to Siena via Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 20h 1m. Alternatively, you can take a bus from Pºeuropa-Av.Montes De Oca to Siena via Intercambiador De Plaza Castilla, Avenida De Asturias - Plaza De Castilla, Cibeles, Cibeles - Ayuntamiento, Estación Sur, Madrid, Genoa, and Florence Villa Constanza Bus Station in around 28h 38m.
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport
- Ave. Duration
- 2h 22m
- When
- Every day
- Estimated price
- €55–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €55–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- €65–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport via Barcelona
- Ave. Duration
- 4h 45m
- When
- Thursday
- Estimated price
- €45–180
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- €45–120
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport
- Ave. Duration
- 2h 22m
- When
- Every day
- Estimated price
- €55–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €55–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- €65–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport via Barcelona
- Ave. Duration
- 4h 45m
- When
- Thursday
- Estimated price
- €45–180
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- €45–120
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Pisa International Airport
- Ave. Duration
- 2h 15m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- €55–170
Flights from Adolfo Suárez Madrid–Barajas Airport to Pisa International Airport via Ibiza
- Ave. Duration
- 3h 55m
- When
- Monday to Friday
- Estimated price
- €55–170
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €55–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €45–130
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport via Palma Mallorca
- Ave. Duration
- 4h 10m
- When
- Wednesday
- Estimated price
- €45–130
- Website
- aireuropa.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 15m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €50–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 24m
- When
- Every day
- Estimated price
- €45–160
- Website
- ita-airways.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €45–160
- Website
- flyulendo.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- €28–120
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- 4 times a day
- Estimated price
- €55–90
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–10
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–13
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 35m
- Frequency
- Every 3 hours
- Estimated price
- €30–55
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- https://www.renfe.com/es/en
- Phone
- +34 900 926 851
- [email protected]
- Website
- iryo.eu
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- https://iryo.eu/en/home
- Phone
- +34 900 759 781
- Website
- ouigo.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- https://www.ouigo.com/es/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- https://www.renfe.com/es/en
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 6m
- Frequency
- Twice daily
- Estimated price
- €80–130
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 42m
- Frequency
- Twice daily
- Estimated price
- €140–230
- Website
- https://www.renfe.com/es/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €45–90
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 15 minutes
- Estimated price
- €13–27
- Schedules at
- trenitalia.com
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 42m
- Frequency
- Every 15 minutes
- Estimated price
- €35–80
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 2h 41m
- Frequency
- 4 times a day
- Estimated price
- €35–80
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- 5 times a day
- Estimated price
- €11–23
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- 3 times a day
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- 3 times a day
- Estimated price
- €9–20
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- €28–60
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 4 13 94 30 50
- Website
- zou.maregionsud.fr
Train from Marseille-Saint-Charles to Nice-Saint-Augustin
- Ave. Duration
- 2h 33m
- Frequency
- Hourly
- Estimated price
- €55–110
- Website
- https://zou.maregionsud.fr/en/
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Madrid to Genoa
- Ave. Duration
- 21h
- Frequency
- Once daily
- Estimated price
- €130–220
- Website
- https://www.flixbus.co.uk
Bus from Genoa to Florence Villa Constanza Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Every 3 hours
- Estimated price
- €19–35
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €5–10
- Website
- https://www.flixbus.co.uk
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €5–11
- Website
- https://www.blablacar.co.uk/bus
Bus from Nice - Airport Bus Station Terminal 1 to Siena
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- €45–85
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Méndez Álvaro Estación Sur to Padova
- Ave. Duration
- 27h 34m
- Frequency
- Once a week
- Estimated price
- €120–160
- Schedules at
- tabitatour.ro
- Phone
- +39 098 3520 315
- [email protected]
- Website
- simetbus.it
Bus from Padova to Florence
- Ave. Duration
- 2h 56m
- Frequency
- 3 times a week
- Estimated price
- €25–29
- Schedules at
- simetbus.it
- Phone
- +39 800 142 424
- [email protected]
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
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More Questions & Answers
San Sebastián de los Reyes to Siena bus services, operated by Tabita Tour, arrive at Padova station.
San Sebastián de los Reyes to Siena train services, operated by Renfe AVE, arrive at Barcelona-Sants station.
Yes, the driving distance between San Sebastián de los Reyes to Siena is 1672 km. It takes approximately 17h 14m to drive from San Sebastián de los Reyes to Siena.
Book your San Sebastián de los Reyes to Siena train tickets online with Omio.
Book your San Sebastián de los Reyes to Siena bus tickets online with Omio.
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