There are 6 ways to get from San Sebastián de los Reyes to Lyon by plane, train (Renfe, Ouigo), bus, car, or train (Renfe, TGV, Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Lyon–Saint Exupéry Airport (LYS)plane MAD - LYS
4h 43m€63–258Train via Barcelona
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain 9737
9h 47m€127–273Bus
- Take the bus from Madrid - Barajas Airport T4 to Lyon - Gerland Bus Stationbus BlaBlaCar Bus
17h 57m€86–162Drive 1,187.7 km
- Drive from San Sebastián de los Reyes to Lyoncar 1,187.7 km
11h 38m€194–279Train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Avignon Tgvtrain 9725
- Take the train from Avignon Tgv to Lyon Part Dieutrain Tgv
10h 59m€159–263Bus via Madrid
- Take the bus from Madrid to Lyonbus FlixBus N748 / ...
18h 45m€103–164
San Sebastián de los Reyes to Lyon by train
Comparing Your Travel Options
The cheapest way to get from San Sebastián de los Reyes to Lyon is to bus which costs €85 - €170 and takes 17h 57m.
The fastest way to get from San Sebastián de los Reyes to Lyon is to fly which takes 4h 43m and costs €60 - €260.
No, there is no direct bus from San Sebastián de los Reyes to Lyon station. However, there are services departing from Av.España-Centro De Mayores and arriving at Lyon - Gerland Bus Station via Madrid - Barajas Airport T4. The journey, including transfers, takes approximately 17h 57m.
No, there is no direct train from San Sebastián de los Reyes to Lyon. However, there are services departing from Alcobendas-San Sebastián de los Reyes and arriving at Lyon Part Dieu via Madrid-Puerta de Atocha-Almudena Grandes and Barcelona-Sants. The journey, including transfers, takes approximately 9h 47m.
The distance between San Sebastián de los Reyes and Lyon is 944 km. The road distance is 1187.7 km.
The best way to get from San Sebastián de los Reyes to Lyon without a car is to train via Barcelona which takes 9h 47m and costs €120 - €280.
It takes approximately 4h 43m to get from San Sebastián de los Reyes to Lyon, including transfers.
San Sebastián de los Reyes to Lyon bus services, operated by BlaBlaCar Bus, depart from Madrid - Barajas Airport T4 station.
San Sebastián de los Reyes to Lyon train services, operated by Renfe AVE, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
The best way to get from San Sebastián de los Reyes to Lyon is to fly which takes 4h 43m and costs €60 - €260. Alternatively, you can train via Barcelona, which costs €120 - €280 and takes 9h 47m, you could also bus, which costs €85 - €170 and takes 17h 57m.
What companies run services between San Sebastián de los Reyes, Spain and Lyon, France?
Volotea, Iberia, and two other airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Lyon–Saint Exupéry Airport (LYS) 4 times a day. Alternatively, you can take a train from Alcobendas-San Sebastián de los Reyes to Lyon Part Dieu via Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, and Barcelona-Sants in around 9h 47m.
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- €40–170
Flights from Adolfo Suárez Madrid–Barajas Airport to Lyon–Saint Exupéry Airport via Barcelona
- Ave. Duration
- 3h 55m
- When
- Friday
- Estimated price
- €100–240
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- €40–170
Flights from Adolfo Suárez Madrid–Barajas Airport to Lyon–Saint Exupéry Airport via Barcelona
- Ave. Duration
- 3h 55m
- When
- Friday
- Estimated price
- €100–240
- Website
- easyjet.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Friday, and Sunday
- Estimated price
- €45–200
- Website
- volotea.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 45m
- When
- Monday and Friday
- Estimated price
- €27–170
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €85–150
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €55–95
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 27m
- Frequency
- Hourly
- Estimated price
- €45–80
- Website
- Ouigo
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–110
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 6m
- Frequency
- Twice daily
- Estimated price
- €80–120
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Avignon Tgv
- Ave. Duration
- 8h 2m
- Frequency
- Twice daily
- Estimated price
- €130–190
- Website
- Renfe Viajeros
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €45–70
- Website
- TGV inOui
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 6m
- Frequency
- 4 times a day
- Estimated price
- €35–70
- Website
- Oui.SNCF
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 8m
- Frequency
- Twice daily
- Estimated price
- €27–40
- Website
- Trenitalia
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 5m
- Frequency
- Twice a week
- Estimated price
- €40–65
- Website
- Belgian Railways
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Madrid - Barajas Airport T4 to Lyon - Gerland Bus Station
- Ave. Duration
- 16h 45m
- Frequency
- Every 4 hours
- Estimated price
- €85–150
- Website
- BlaBlaCar Bus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Madrid - Barajas Airport T4 to Lyon - Gerland Bus Station
- Ave. Duration
- 17h 31m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Flixbus
Bus from Madrid to Lyon
- Ave. Duration
- 16h 40m
- Frequency
- 3 times a day
- Estimated price
- €100–160
- Website
- Flixbus
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
San Sebastián de los Reyes to Lyon bus services, operated by BlaBlaCar Bus, arrive at Lyon - Gerland Bus Station.
San Sebastián de los Reyes to Lyon train services, operated by Renfe AVE, arrive at Barcelona-Sants station.
Yes, the driving distance between San Sebastián de los Reyes to Lyon is 1188 km. It takes approximately 11h 38m to drive from San Sebastián de los Reyes to Lyon.
Book your San Sebastián de los Reyes to Lyon train tickets online with Omio.
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