There are 8 ways to get from San Sebastián de los Reyes to Siena by plane, train, train (Renfe, Ouigo, Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Florence Peretola Airport (FLR)plane MAD - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 45m€75–180Fly to Pisa International Airport, train
cheapest- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Pisa International Airport (PSA)plane MAD - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
6h 42m€49–248Train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
19h 44m€218–449Bus
- Take the bus from Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) to Barcelona, Estació d'Autobusos Nordbus
- Take the bus from Barcelona to Florencebus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 443 / ...
26h 22m€146–231Drive 1,671.9 km
- Drive from San Sebastián de los Reyes to Sienacar 1,671.9 km
17h 14m€272–393Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Bologna Guglielmo Marconi Airport (BLQ)plane MAD - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
7h 25m€72–230Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the bus from Marseille, Gare de Marseille-Saint-Charles to Florence Villa Constanza Bus Stationbus
- Take the train from Firenze S.M.N. to Sienatrain Re
22h 40m€205–316Bus, train
- Take the bus from Méndez Álvaro Estación Sur to Padovabus
- Take the train from Padova to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
33h 24m€153–220
San Sebastián de los Reyes to Siena by train
Comparing Your Travel Options
The cheapest way to get from San Sebastián de los Reyes to Siena is to fly and train which costs €70 - €180 and takes 6h 45m.
The fastest way to get from San Sebastián de los Reyes to Siena is to fly and train which takes 6h 42m and costs €45 - €250.
No, there is no direct bus from San Sebastián de los Reyes to Siena. However, there are services departing from Av.España-Centro De Mayores and arriving at Siena via Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid), Barcelona and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 26h 22m.
No, there is no direct train from San Sebastián de los Reyes to Siena. However, there are services departing from Alcobendas-San Sebastián de los Reyes and arriving at Siena via Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, Lyon Part Dieu, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 19h 44m.
The distance between San Sebastián de los Reyes and Siena is 1381 km. The road distance is 1671.9 km.
The best way to get from San Sebastián de los Reyes to Siena without a car is to train which takes 19h 44m and costs €210 - €450.
It takes approximately 6h 45m to get from San Sebastián de los Reyes to Siena, including transfers.
San Sebastián de los Reyes to Siena bus services, operated by ALSA, depart from Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) station.
San Sebastián de los Reyes to Siena train services, operated by Renfe AVE, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
The best way to get from San Sebastián de los Reyes to Siena is to train which takes 19h 44m and costs €210 - €450. Alternatively, you can bus, which costs €140 - €240 and takes 26h 22m.
What companies run services between San Sebastián de los Reyes, Spain and Siena, Italy?
You can take a train from Alcobendas-San Sebastián de los Reyes to Siena via Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 19h 44m. Alternatively, you can take a bus from Av.España-Centro De Mayores to Siena via Av.Hispanidad-Aeropuerto T4, Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid), Barcelona, Estació d'Autobusos Nord, Barcelona, and Florence Villa Constanza Bus Station in around 26h 22m.
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport
- Ave. Duration
- 2h 19m
- When
- Every day
- Estimated price
- €60–200
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 4h 5m
- When
- Saturday to Sunday
- Estimated price
- €60–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- €50–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport via Barcelona
- Ave. Duration
- 4h 45m
- When
- Monday and Wednesday
- Estimated price
- €45–170
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport
- Ave. Duration
- 2h 19m
- When
- Every day
- Estimated price
- €60–200
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 4h 5m
- When
- Saturday to Sunday
- Estimated price
- €60–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- €50–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport via Barcelona
- Ave. Duration
- 4h 45m
- When
- Monday and Wednesday
- Estimated price
- €45–170
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Pisa International Airport
- Ave. Duration
- 2h 15m
- When
- Monday, Thursday, and Sunday
- Estimated price
- €60–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 20m
- When
- Tuesday, Friday, Sunday, Monday, and Wednesday
- Estimated price
- €45–170
- Website
- flyulendo.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Pisa International Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- €14–120
- Website
- volotea.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Pisa International Airport via Toulouse
- Ave. Duration
- 3h 55m
- When
- Friday
- Estimated price
- €45–230
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- 4 times a day
- Estimated price
- €50–75
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €90–160
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €55–95
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 27m
- Frequency
- Hourly
- Estimated price
- €45–80
- Website
- Ouigo
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–110
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 6m
- Frequency
- Twice daily
- Estimated price
- €80–120
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 42m
- Frequency
- Twice daily
- Estimated price
- €140–210
- Website
- Renfe Viajeros
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €40–75
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Padova to Firenze S.M.N.
- Ave. Duration
- 1h 43m
- Frequency
- Hourly
- Estimated price
- €29–50
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 58m
- Frequency
- 4 times a day
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 38 min
- Frequency
- 5 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
Train from Padova to Firenze S.M.N.
- Ave. Duration
- 1h 53m
- Frequency
- Once daily
- Estimated price
- €25–45
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Twice daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
- Phone
- +34 910 207 007
- Website
- ALSA
Bus from Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) to Barcelona, Estació d'Autobusos Nord
- Ave. Duration
- 7h 50m
- Frequency
- Every 3 hours
- Estimated price
- €50–80
- Website
- ALSA
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Barcelona to Florence
- Ave. Duration
- 14h 30m
- Frequency
- Twice daily
- Estimated price
- €90–140
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- €5–9
- Website
- Flixbus
Bus from Marseille, Gare de Marseille-Saint-Charles to Florence Villa Constanza Bus Station
- Ave. Duration
- 9h 5m
- Frequency
- Once daily
- Estimated price
- €50–85
- Website
- Flixbus
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Méndez Álvaro Estación Sur to Padova
- Ave. Duration
- 27h 34m
- Frequency
- Once a week
- Estimated price
- €120–160
- Schedules at
- tabitatour.ro
- Phone
- +39 800 142 424
- [email protected]
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Schedules at
- at-bus.it
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Booking & Getting There
San Sebastián de los Reyes to Siena bus services, operated by ALSA, arrive at Barcelona, Estació d'Autobusos Nord station.
San Sebastián de los Reyes to Siena train services, operated by Renfe AVE, arrive at Barcelona-Sants station.
Yes, the driving distance between San Sebastián de los Reyes to Siena is 1672 km. It takes approximately 17h 14m to drive from San Sebastián de los Reyes to Siena.
Book your San Sebastián de los Reyes to Siena train tickets online with Omio.
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