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How to get fromSan Ysidro to Santa Mariaby train (Amtrak), bus (Greyhound, Flixbus), car, plane, or bus

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There are 6 ways to get from San Ysidro to Santa Maria by train (Amtrak), bus (Greyhound, Flixbus), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from San Diego to Guadalupe Amtrak Stationtrain train Pacific Surfliner
    10h 54m
    $98–227

  2. Bus via Santa Barbara

    cheapest
    1. Take the bus from San Ysidro to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Santa Barbara Bus Stopbus bus
    3. Take the bus from Chapala at Figueroa to Santa Maria Transit Centerbus bus
    10h 54m
    $49–78

  3. Drive 291.3 mi

    1. Drive from San Ysidro to Santa Mariacar car 291.3 mi
    5h 13m
    $54–77

  4. Fly to Santa Barbara Municipal Airport, bus

    1. Fly from San Diego International Airport (SAN) to Santa Barbara Municipal Airport (SBA)plane plane SAN - SBA
    2. Take the bus from Santa Barbara Airport to Santa Maria Airport, CAbus bus
    6h 35m
    $140–317

  5. Bus

    1. Take the bus from San Diego to LAX Terminal 3 Shared Rides Stopbus bus reLAXsan
    2. Take the bus from Los Angeles Airport, CA to Santa Maria Airport, CAbus bus
    11h 15m
    $146–233

  6. Fly to San Luis Obispo County Regional Airport, bus

    1. Fly from San Diego International Airport (SAN) to San Luis Obispo County Regional Airport (SBP)plane plane SAN - SBP
    2. Take the bus from Government Center to Santa Maria Transit Centerbus bus
    6h 38m
    $178–376

San Ysidro to Santa Maria by tram, train, and bus (Amtrak)

Calendar14Weekly Services
Duration10h 54mAverage Duration
Ticket$98Cheapest Price
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Questions & Answers

Map of how to get from San Ysidro to Santa Maria.ExpandLaunch map view
  • Distance: 346.4 mi
  • Duration: 10h 54m

What companies run services between San Ysidro, CA, USA and Santa Maria, Santa Barbara County, CA, USA?

Amtrak operates a train from San Diego to Guadalupe Amtrak Station twice daily. Tickets cost $95–210 and the journey takes 7h 50m. Alternatively, you can take a bus from San Ysidro to Santa Maria Transit Center via Los Angeles Union Station, Santa Barbara Bus Stop, Cabrillo & Anacapa, Chapala & Anapamu, and Chapala at Figueroa in around 10h 54m.

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