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How to get fromSandestin to Florida Keysby plane, taxi, bus, train, car, or shuttle

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There are 7 ways to get from Sandestin to Florida Keys by plane, taxi, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Key West International Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW)plane plane VPS - EYW
    7h 37m
    $190–463

  2. Drive 719.9 mi

    cheapest
    1. Drive from Sandestin to Florida Keyscar car 719.9 mi
    14h 11m
    $132–190

  3. Taxi, bus, train

    1. Take the taxi from Sandestin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Plant Citybus bus
    3. Take the train from Lakeland to Miami Amtrak Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    20h 14m
    $350–519

  4. Drive to Pensacola International Airport, fly to Key West International Airport

    1. Drive from Sandestin to Pensacola-Airport-PNScar car
    2. Fly from Pensacola International Airport (PNS) to Key West International Airport (EYW)plane plane PNS - EYW
    8h 16m
    $138–390

  5. Fly Destin–Fort Walton Beach Airport to Miami International Airport, shuttle

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA)plane plane VPS - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    7h 49m
    $265–573

  6. Drive to Pensacola International Airport, fly to Miami International Airport, shuttle

    1. Drive from Sandestin to Pensacola-Airport-PNScar car
    2. Fly from Pensacola International Airport (PNS) to Miami International Airport (MIA)plane plane PNS - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    8h 52m
    $213–500

  7. Taxi, bus

    1. Take the taxi from Sandestin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Miamibus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    21h 46m
    $227–306

Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW) flights

Calendar28Weekly Planes
Duration5h 4mAverage Duration
Ticket$56Cheapest Price
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Questions & Answers

Map of how to get from Sandestin to Florida Keys.ExpandLaunch map view
  • Distance: 548.9 mi
  • Duration: 7h 37m

What companies run services between Sandestin, FL, USA and Florida Keys, FL, USA?

Delta and American Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW) 4 times a day.

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