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How to get fromSandestin to Florida Keysby plane, taxi, bus, train, car, or shuttle

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There are 9 ways to get from Sandestin to Florida Keys by plane, taxi, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Key West International Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW)plane plane VPS - EYW
    7h 12m
    $190–473

  2. Drive  719.9 mi

    cheapest
    1. Drive from Sandestin to Florida Keyscar car 719.9 mi
    14h 11m
    $132–190

  3. Taxi, bus, train

    1. Take the taxi from Sandestin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Plant Citybus bus
    3. Take the train from Lakeland to Miami Amtrak Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    20h 14m
    $403–554

  4. Taxi to Northwest Florida Beaches International Airport, fly to Key West International Airport

    1. Take the taxi from Sandestin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Key West International Airport (EYW)plane plane ECP - EYW
    8h 12m
    $261–584

  5. Drive to Pensacola International Airport, fly to Key West International Airport

    1. Drive from Sandestin to Pensacola-Airport-PNScar car
    2. Fly from Pensacola International Airport (PNS) to Key West International Airport (EYW)plane plane PNS - EYW
    7h 58m
    $143–420

  6. Fly Destin–Fort Walton Beach Airport to Miami International Airport, shuttle

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA)plane plane VPS - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    7h 52m
    $265–593

  7. Drive to Pensacola International Airport, fly to Miami International Airport, shuttle

    1. Drive from Sandestin to Pensacola-Airport-PNScar car
    2. Fly from Pensacola International Airport (PNS) to Miami International Airport (MIA)plane plane PNS - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    8h 48m
    $218–530

  8. Drive to Pensacola International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Drive from Sandestin to Pensacola-Airport-PNScar car
    2. Fly from Pensacola International Airport (PNS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane PNS - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 19m
    $323–510

  9. Taxi, bus

    1. Take the taxi from Sandestin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Miamibus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    21h 46m
    $230–301

Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW) flights

Calendar33Weekly Planes
Duration4h 47mAverage Duration
Ticket$54Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sandestin to Florida Keys.ExpandLaunch map view
  • Distance: 548.9 mi
  • Duration: 7h 12m

What companies run services between Sandestin, FL, USA and Florida Keys, FL, USA?

American Airlines and Delta fly from Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW) 5 times a day.

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