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How to get fromSandusky, OH to Chicagoby train (Amtrak), train, bus, car, plane, or bus (Greyhound)

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There are 8 ways to get from Sandusky, OH to Chicago by train (Amtrak), train, bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Sandusky Amtrak Station to Chicago Union Stationtrain train Lake Shore Limited / ...
    6h 2m
    $95–196

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Sandusky Bus Stop to Chicago Bus Stationbus bus Greyhound US0164
    7h 8m
    $50–96

  3. Train, bus (Amtrak)

    1. Take the train from Sandusky Amtrak Station to Toledotrain train Lake Shore Limited / ...
    2. Take the bus from Toledo to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    6h 25m
    $105–171

  4. Drive 290.2 mi

    1. Drive from Sandusky, OH to Chicagocar car 290.2 mi
    4h 51m
    $53–77

  5. Bus to Cleveland-Hopkins International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Sandusky Bus Stop to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Chicago Midway International Airport (MDW)plane plane CLE - MDW
    4h 19m
    $78–400

  6. Bus to Cleveland-Hopkins International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Sandusky Bus Stop to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Chicago O'Hare International Airport (ORD)plane plane CLE - ORD
    4h 44m
    $388–830

  7. Train, bus to Detroit, fly to Chicago Midway International Airport

    1. Take the train from Sandusky Amtrak Station to Toledotrain train
    2. Take the bus from Toledo to Dearbornbus bus
    3. Fly from Detroit (DTW) to Chicago Midway International Airport (MDW)plane plane DTW - MDW
    7h 7m
    $178–543

  8. Train, bus to Detroit, fly to Chicago O'Hare International Airport

    1. Take the train from Sandusky Amtrak Station to Toledotrain train
    2. Take the bus from Toledo to Dearbornbus bus
    3. Fly from Detroit (DTW) to Chicago O'Hare International Airport (ORD)plane plane DTW - ORD
    7h 24m
    $198–733

Cleveland-Hopkins International Airport (CLE) to Chicago Midway International Airport (MDW) flights

Calendar33Weekly Planes
Duration1h 27mAverage Duration
Ticket$59Cheapest Price
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Questions & Answers

Map of how to get from Sandusky, OH to Chicago.ExpandLaunch map view
  • Distance: 280.8 mi
  • Duration: 6h 2m

What companies run services between Sandusky, OH, USA and Chicago, IL, USA?

Amtrak operates a train from Sandusky Amtrak Station to Chicago Union Station 3 times a day. Tickets cost $90–190 and the journey takes 5h 59m. Alternatively, Greyhound USA operates a bus from Sandusky Bus Stop to Chicago Bus Station once daily. Tickets cost $45–90 and the journey takes 7h 5m.

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