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How to get fromSandusky to Charlestonby bus, plane, train (Amtrak), bus (Greyhound), car, or train

Find Transport to Charleston

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There are 6 ways to get from Sandusky to Charleston by bus, plane, train (Amtrak), bus (Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Cleveland-Hopkins International Airport, fly

    best
    1. Take the bus from Sandusky Bus Stop to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Charleston International Airport (CHS)plane plane CLE - CHS
    7h 53m
    $115–620
  2. Train, bus to Akron, fly

    cheapest
    1. Take the train from Sandusky Amtrak Station to Cleveland Amtraktrain train
    2. Take the bus from Cleveland to Akronbus bus
    3. Fly from Akron (CAK) to Charleston International Airport (CHS)plane plane CAK - CHS
    9h 11m
    $114–522
  3. Train (Amtrak)

    1. Take the train from Sandusky Amtrak Station to Petersburg Amtrak Stationtrain train Floridian
    2. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    23h 39m
    $576–880
  4. Bus (Greyhound)

    1. Take the bus from Sandusky Bus Stop to Toledo Bus Stopbus bus
    2. Take the bus from Toledo Bus Stop to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Charleston Bus Stationbus bus
    28h 7m
    $178–280
  5. Drive  722.7 mi

    1. Drive from Sandusky to Charlestoncar car 722.7 mi
    13h 29m
    $128–185
  6. Train, bus to Detroit, fly

    1. Take the train from Sandusky Amtrak Station to Toledotrain train
    2. Take the bus from Toledo to Dearbornbus bus
    3. Fly from Detroit (DTW) to Charleston International Airport (CHS)plane plane DTW - CHS
    8h 52m

Sandusky to Charleston by bus (Greyhound)

Calendar7Weekly Buses
Duration28h 7mAverage Duration
Ticket$178Cheapest Price
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Comparing Your Travel Options

What companies run services between Sandusky, OH, USA and Charleston, SC, USA?

You can take a train from Sandusky Amtrak Station to Charleston via Petersburg Amtrak Station and Charleston Amtrak Station in around 23h 39m. Alternatively, you can take a bus from Sandusky Bus Stop to Transit Mall via Toledo Bus Stop, Charlotte Bus Station, Camden, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 28h 7m.

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Need to know: Greyhound

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