There are 7 ways to get from Sandusky to Chicago Union Station by train (Amtrak), train, bus, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Sandusky Amtrak Station to Chicago Union Stationtrain Lake Shore Limited / ...
5h 59m$70–170Bus (Greyhound)
cheapest- Take the bus from Sandusky Bus Stop to Chicago Bus Stationbus Greyhound US0164
7h 14m$45–75Train, bus (Amtrak)
- Take the train from Sandusky Amtrak Station to Toledotrain Lake Shore Limited / ...
- Take the bus from Toledo to Chicago Union Stationbus Amtrak Thruway Connecting Service
6h 22m$77–127Drive 289.8 mi
- Drive from Sandusky to Chicago Union Stationcar 289.8 mi
4h 50m$53–77Bus to Cleveland-Hopkins International Airport, fly to Chicago Midway International Airport
- Take the bus from Sandusky Bus Stop to Cleveland Bus Stationbus
- Fly from Cleveland-Hopkins International Airport (CLE) to Chicago Midway International Airport (MDW)plane CLE - MDW
4h 25m$68–401Bus to Cleveland-Hopkins International Airport, fly to Chicago O'Hare International Airport
- Take the bus from Sandusky Bus Stop to Cleveland Bus Stationbus
- Fly from Cleveland-Hopkins International Airport (CLE) to Chicago O'Hare International Airport (ORD)plane CLE - ORD
4h 51m$373–821Train, bus to Detroit, fly to Chicago Midway International Airport
- Take the train from Sandusky Amtrak Station to Toledotrain
- Take the bus from Toledo to Dearbornbus
- Fly from Detroit (DTW) to Chicago Midway International Airport (MDW)plane DTW - MDW
7h 8m$165–522
Sandusky to Chicago Union Station by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Sandusky to Chicago Union Station is to bus which costs $45 - $75 and takes 7h 14m.
The fastest way to get from Sandusky to Chicago Union Station is to bus and fly which takes 4h 25m and costs $65 - $410.
Yes, there is a direct bus departing from Sandusky Bus Stop and arriving at Chicago Bus Station station. Services depart once daily, and operate every day. The journey takes approximately 7h 5m.
Yes, there is a direct train departing from Sandusky Amtrak Station station and arriving at Chicago Union Station station. Services depart three times a day, and operate every day. The journey takes approximately 5h 59m.
The distance between Sandusky and Chicago Union Station is 281 miles. The road distance is 291.5 miles.
The best way to get from Sandusky to Chicago Union Station without a car is to train which takes 5h 59m and costs $70 - $170.
The train from Sandusky Amtrak Station to Chicago Union Station takes 5h 59m including transfers and departs three times a day.
Sandusky to Chicago Union Station bus services, operated by Greyhound USA, depart from Sandusky Bus Stop station.
Sandusky to Chicago Union Station train services, operated by Amtrak, depart from Sandusky Amtrak Station.
The best way to get from Sandusky to Chicago Union Station is to train which takes 5h 59m and costs $70 - $170. Alternatively, you can bus, which costs $45 - $75 and takes 7h 14m.
What companies run services between Sandusky, OH, USA and Chicago Union Station, IL, USA?
Amtrak operates a train from Sandusky Amtrak Station to Chicago Union Station 3 times a day. Tickets cost $70–170 and the journey takes 5h 59m. Alternatively, Greyhound USA operates a bus from Sandusky Bus Stop to Chicago Bus Station once daily. Tickets cost $45–75 and the journey takes 7h 5m.
- Website
- southwest.com
Flights from Cleveland-Hopkins International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $55–380
Flights from Detroit to Chicago Midway International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $55–380
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Sandusky Amtrak Station to Chicago Union Station
- Ave. Duration
- 5h 59m
- Frequency
- 3 times a day
- Estimated price
- $70–170
- Website
- Amtrak
Train from Sandusky Amtrak Station to Toledo
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $12–27
- Website
- Amtrak
Train from Sandusky Amtrak Station to Toledo
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $12–27
- Website
- Amtrak
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Toledo to Chicago Union Station
- Ave. Duration
- 4h 22m
- Frequency
- Twice a week
- Estimated price
- $65–100
- Website
- Amtrak
Bus from Toledo to Dearborn
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $19–28
- Website
- Amtrak
Want to know more about travelling around United States
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Booking & Getting There
Sandusky to Chicago Union Station bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Chicago Union Station is 1h behind Sandusky. It is currently 3:19 PM in Sandusky and 2:19 PM in Chicago Union Station.
Sandusky to Chicago Union Station train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Sandusky to Chicago Union Station is 291 miles. It takes approximately 4h 50m to drive from Sandusky to Chicago Union Station.
Book your Sandusky to Chicago Union Station train tickets online with Omio.
Book your Sandusky to Chicago Union Station bus tickets online with Omio and FlixBus.
There are 1285+ hotels available in Chicago Union Station.



