There are 6 ways to get from Sandusky to Louisville by bus (Greyhound, Amtrak), car, bus, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Sandusky Bus Stop to Toledo Bus Stopbus
- Take the bus from Toledo to Indianapolisbus
- Take the bus from Indianapolis Union Station to Louisville, KYbus
9h 10m$52–124Drive 298.6 mi
cheapest- Drive from Sandusky to Louisvillecar 298.6 mi
6h 3m$51–74Bus to Cleveland-Hopkins International Airport, fly to Louisville International Airport
- Take the bus from Sandusky Bus Stop to Cleveland Bus Stationbus
- Fly from Cleveland-Hopkins International Airport (CLE) to Louisville International Airport (SDF)plane CLE - SDF
7h 14m$134–820Train, bus
- Take the train from Sandusky Amtrak Station to Toledotrain
- Take the bus from Toledo Bus Stop to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Louisville, KYbus
9h 15m$88–145Train, bus to Detroit, fly to Louisville International Airport
- Take the train from Sandusky Amtrak Station to Toledotrain
- Take the bus from Toledo to Dearbornbus
- Fly from Detroit (DTW) to Louisville International Airport (SDF)plane DTW - SDF
7h 49mTrain, bus to Detroit, fly to Blue Grass Airport, drive
- Take the train from Sandusky Amtrak Station to Toledotrain
- Take the bus from Toledo to Dearbornbus
- Fly from Detroit (DTW) to Blue Grass Airport (LEX)plane DTW - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
7h 51m
Sandusky to Louisville by bus
Comparing Your Travel Options
The cheapest way to get from Sandusky to Louisville is to drive which costs $50 - $75 and takes 6h 3m.
The fastest way to get from Sandusky to Louisville is to drive which takes 6h 3m and costs $50 - $75.
No, there is no direct bus from Sandusky to Louisville. However, there are services departing from Sandusky Bus Stop and arriving at Louisville, KY via Toledo and Indianapolis Union Station. The journey, including transfers, takes approximately 9h 10m.
The distance between Sandusky and Louisville is 390 miles. The road distance is 300.4 miles.
The best way to get from Sandusky to Louisville without a car is to bus which takes 9h 10m and costs $50 - $130.
It takes approximately 9h 10m to get from Sandusky to Louisville, including transfers.
Sandusky to Louisville bus services, operated by Greyhound USA, depart from Sandusky Bus Stop station.
Sandusky to Louisville bus services, operated by Greyhound USA, arrive at Toledo Bus Stop station.
Yes, the driving distance between Sandusky to Louisville is 300 miles. It takes approximately 6h 3m to drive from Sandusky to Louisville.
Book your Sandusky to Louisville bus tickets online with Omio.
What companies run services between Sandusky, OH, USA and Louisville, KY, USA?
You can take a bus from Sandusky Bus Stop to Louisville, KY via Toledo and Indianapolis Union Station in around 9h 10m.
- Website
- delta.com
Flights from Cleveland-Hopkins International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $120–800
Flights from Detroit to Louisville International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $120–850
Flights from Detroit to Blue Grass Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $70–470
- Website
- united.com
Flights from Cleveland-Hopkins International Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 22m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $170–950
Flights from Cleveland-Hopkins International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $150–900
- Website
- southwest.com
Flights from Cleveland-Hopkins International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h 52m
- When
- Saturday
- Estimated price
- $150–900
Flights from Cleveland-Hopkins International Airport to Louisville International Airport via Chicago Midway
- Ave. Duration
- 5h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–850
Flights from Cleveland-Hopkins International Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 5h 58m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $180–950
- Website
- aa.com
Flights from Cleveland-Hopkins International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $150–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Sandusky Amtrak Station to Toledo
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $25–40
- Website
- Amtrak
Train from Sandusky Amtrak Station to Toledo
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $25–40
- Website
- Amtrak
Train from Sandusky Amtrak Station to Toledo
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $25–40
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Sandusky Bus Stop to Toledo Bus Stop
- Ave. Duration
- 1h 10m
- Frequency
- Twice daily
- Estimated price
- $9–14
- Website
- Greyhound
Bus from Sandusky Bus Stop to Cleveland Bus Station
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Toledo Bus Stop to Indianapolis Union Station
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- Greyhound
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Toledo to Indianapolis
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- Barons Bus
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Toledo to Dearborn
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Website
- Amtrak
Bus from Toledo to Dearborn
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Website
- Amtrak
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 613+ hotels available in Louisville.
















