There are 6 ways to get from Sanford to Buffalo by train, plane, bus (Flixbus, Greyhound), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, fly to Buffalo Niagara International Airport
best- Take the train from Sanford to Sand Lake Roadtrain
- Fly from Orlando (MCO) to Buffalo Niagara International Airport (BUF)plane MCO - BUF
5h 53m$147–335Bus
- Take the bus from Deltona to Washington Union Stationbus
- Take the bus from Washington Union Station to Newark Penn Stationbus
- Take the bus from Newark Penn Station to Buffalobus
29h 54m$233–421Train (Amtrak)
- Take the train from Deland to Ny Moynihan Train Hall At Penn Stationtrain Silver Meteor
- Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain Empire Service / ...
32h 5m$483–1,043Drive 1,155.5 mi
- Drive from Sanford to Buffalocar 1,155.5 mi
19h 32m$211–305Train, fly to Rochester, bus
- Take the train from Sanford to Sand Lake Roadtrain
- Fly from Orlando (MCO) to Rochester (ROC)plane MCO - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
7h 7m$264–650Train, bus
- Take the train from Deland to Pittsburgh Amtrak Stationtrain Floridian
- Take the bus from Pittsburgh, Pa to Buffalo, Nybus 510
38h 1m$418–993
Sanford to Buffalo by train (Amtrak)
Questions & Answers
The cheapest way to get from Sanford to Buffalo is to train and fly which costs $140 - $340 and takes 5h 53m.
The fastest way to get from Sanford to Buffalo is to train and fly which takes 5h 53m and costs $140 - $340.
No, there is no direct bus from Sanford to Buffalo. However, there are services departing from Deltona and arriving at Buffalo via Washington Union Station and Newark Penn Station. The journey, including transfers, takes approximately 29h 54m.
No, there is no direct train from Sanford to Buffalo. However, there are services departing from Sanford and arriving at Buffalo via Deland and Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 32h 5m.
The distance between Sanford and Buffalo is 1078 miles. The road distance is 1162.3 miles.
The best way to get from Sanford to Buffalo without a car is to bus which takes 29h 54m and costs $230 - $430.
It takes approximately 5h 53m to get from Sanford to Buffalo, including transfers.
Sanford to Buffalo bus services, operated by Flixbus USA, depart from Deltona station.
Sanford to Buffalo train services, operated by Amtrak, depart from Deland station.
The best way to get from Sanford to Buffalo is to bus which takes 29h 54m and costs $230 - $430. Alternatively, you can train, which costs $480 - $1,100 and takes 32h 5m.
What companies run services between Sanford, FL, USA and Buffalo, NY, USA?
You can take a vehicle from Sanford to Buffalo via Deltona, Washington Union Station, and Newark Penn Station in around 29h 54m. Alternatively, you can take a train from Sanford to Buffalo via Deland and Ny Moynihan Train Hall At Penn Station in around 32h 5m.
- Website
- southwest.com
Flights from Orlando to Buffalo Niagara International Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- $130–650
Flights from Orlando to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 4h 27m
- When
- Tuesday, Wednesday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $130–650
Flights from Orlando to Rochester
- Ave. Duration
- 2h 37m
- When
- Every day
- Estimated price
- $150–700
Flights from Orlando to Rochester via Baltimore
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $150–700
- Website
- jetblue.com
Flights from Orlando to Buffalo Niagara International Airport
- Ave. Duration
- 2h 44m
- When
- Every day
- Estimated price
- $130–650
Flights from Orlando to Rochester
- Ave. Duration
- 2h 46m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $150–700
- Website
- aa.com
Flights from Orlando to Buffalo Niagara International Airport via Charlotte
- Ave. Duration
- 4h 33m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
Flights from Orlando to Rochester via Reagan Washington
- Ave. Duration
- 4h 43m
- When
- Saturday
- Estimated price
- $150–700
- Website
- united.com
Flights from Orlando to Rochester via Washington Dulles
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $150–700
- Website
- flyfrontier.com
Flights from Orlando to Buffalo Niagara International Airport
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- $140–300
- Website
- flybreeze.com
Flights from Orlando to Rochester via Raleigh/Durham
- Ave. Duration
- 5h 29m
- When
- Wednesday and Saturday
- Estimated price
- $280–600
- Phone
- +1 855-724-5411
- [email protected]
- Website
- SunRail
Train from Sanford to Sand Lake Road
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SunRail
Train from Sanford to Sand Lake Road
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SunRail
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Deland to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 21h 10m
- Frequency
- Once daily
- Estimated price
- $340–750
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- 3 times a day
- Estimated price
- $140–290
- Website
- Amtrak
Train from Deland to Pittsburgh Amtrak Station
- Ave. Duration
- 27h 51m
- Frequency
- Once daily
- Estimated price
- $370–800
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Deltona to Washington Union Station
- Ave. Duration
- 16h 20m
- Frequency
- Once daily
- Estimated price
- $130–220
- Schedules at
- Flixbus USA
Bus from Washington Union Station to Newark Penn Station
- Ave. Duration
- 5h
- Frequency
- Hourly
- Estimated price
- $30–60
- Schedules at
- Flixbus USA
Bus from Newark Penn Station to Buffalo
- Ave. Duration
- 7h 55m
- Frequency
- Every 2 hours
- Estimated price
- $60–110
- Schedules at
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- $11–20
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Washington Union Station to Newark Penn Station
- Ave. Duration
- 4h
- Frequency
- Every 3 hours
- Estimated price
- $30–65
- Website
- Greyhound
Bus from Newark Penn Station to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- Twice daily
- Estimated price
- $60–120
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- $11–22
- Website
- Greyhound
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Pittsburgh, Pa to Buffalo, Ny
- Saver
- $45–180
- Flexible
- $80–190
Want to know more about travelling around United States
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More Questions & Answers
Sanford to Buffalo bus services, operated by Flixbus USA, arrive at Washington Union Station.
Sanford to Buffalo train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Sanford to Buffalo is 1162 miles. It takes approximately 19h 32m to drive from Sanford to Buffalo.
There are 235+ hotels available in Buffalo.








