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How to get fromSanford to Charlotteby train, plane, bus (Flixbus), bus, car, tram, or train (Amtrak)

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There are 7 ways to get from Sanford to Charlotte by train, plane, bus (Flixbus), bus, car, tram, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Orlando, fly to Charlotte Douglas International Airport

    best
    1. Take the train from Sanford to Sand Lake Roadtrain train
    2. Fly from Orlando (MCO) to Charlotte Douglas International Airport (CLT)plane plane MCO - CLT
    4h 56m
    $108–349

  2. Bus (Flixbus)

    cheapest
    1. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus FlixBus 2433
    12h 21m
    $80–136

  3. Train, bus

    1. Take the train from Deland to Charleston Amtrak Stationtrain train Silver Meteor
    2. Take the bus from Charleston Bus Station to Charlotte Bus Stationbus bus Greyhound US0643S
    15h 55m
    $153–328

  4. Drive 502.6 mi

    1. Drive from Sanford to Charlottecar car 502.6 mi
    8h 24m
    $92–133

  5. Fly Orlando Sanford to Concord, line 501 tram

    1. Fly from Orlando Sanford (SFB) to Concord (USA)plane plane SFB - USA
    2. Take the tram from JW Clay Blvd Station to 7th St Stationtram tram
    2h 32m
    $91–387

  6. Train, line 34 bus to Daytona Beach International Airport, fly to Charlotte Douglas International Airport

    1. Take the train from Sanford to DeLandtrain train
    2. Take the bus from Deland Sunrail to Amelia Super Stopbus bus
    3. Fly from Daytona Beach International Airport (DAB) to Charlotte Douglas International Airport (CLT)plane plane DAB - CLT
    6h 43m
    $120–710

  7. Train (Amtrak)

    1. Take the train from Deland to Carytrain train Floridian
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train Piedmont / ...
    17h 53m
    $233–493

Sanford to Charlotte by train and bus (Flixbus)

Calendar7Weekly Services
Duration12h 21mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

Map of how to get from Sanford to Charlotte.ExpandLaunch map view
  • Distance: 522.1 mi
  • Duration: 4h 56m

What companies run services between Sanford, FL, USA and Charlotte, NC, USA?

Flixbus USA operates a bus from Orlando Bus Station to Charlotte Bus Station once daily. Tickets cost $75–130 and the journey takes 10h. Alternatively, you can take a train from Sanford to Charlotte Amtrak Station via Deland and Cary in around 17h 53m.

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