Rome2Rio

How to get fromSanford to Des Moinesby plane, bus (Flixbus, Greyhound), train, bus, or car

Find Transport to Des Moines

See all options

There are 6 ways to get from Sanford to Des Moines by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Orlando Sanford

    best
    1. Fly from Orlando Sanford (SFB) to Des Moines (DSM)plane plane SFB - DSM
    3h 7m
    $188–818

  2. Train to Orlando, fly

    cheapest
    1. Take the train from Sanford to Sand Lake Roadtrain train
    2. Fly from Orlando (MCO) to Des Moines (DSM)plane plane MCO - DSM
    7h 36m
    $172–777

  3. Bus

    1. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    31h 46m
    $210–416

  4. Train, bus

    1. Take the train from Deland to Chicago Union Stationtrain train Floridian
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    46h 55m
    $553–1,198

  5. Drive 1,315.9 mi

    1. Drive from Sanford to Des Moinescar car 1,315.9 mi
    23h 18m
    $241–347

  6. Fly from Daytona Beach International Airport

    1. Fly from Daytona Beach International Airport (DAB) to Des Moines (DSM)plane plane DAB - DSM
    9h 12m
    $254–1,128

Sanford to Des Moines by train and bus

Calendar7Weekly Services
Duration31h 46mAverage Duration
Ticket$210Cheapest Price
See schedules

Questions & Answers

Map of how to get from Sanford to Des Moines.ExpandLaunch map view
  • Distance: 1,130.1 mi
  • Duration: 3h 7m

What companies run services between Sanford, FL, USA and Des Moines, IA, USA?

Allegiant Air flies from Orlando Sanford (SFB) to Des Moines (DSM) twice a week. Alternatively, you can take a train from Sanford to Des Moines via LYNX Central, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, Atlanta Bus Station, and St Louis Bus Station in around 31h 46m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers