There are 3 ways to get from Sanford to Gainesville by train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus via Orlando
best- Take the train from Sanford to LYNX Centraltrain SunRail
- Take the bus from Orlando Bus Station to Gainesvillebus FlixBus 2415 / ...
4h 16m$21–34Drive 108.1 mi
cheapest- Drive from Sanford to Gainesvillecar 108.1 mi
2h 19m$20–29Train, bus
- Take the train from Sanford to Sand Lake Roadtrain SunRail
- Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus Miami
4h 34m$34–66
Sanford to Gainesville by train and bus
Questions & Answers
The cheapest way to get from Sanford to Gainesville is to drive which costs $19 - $29 and takes 2h 19m.
The fastest way to get from Sanford to Gainesville is to drive which takes 2h 19m and costs $19 - $29.
The distance between Sanford and Gainesville is 134 miles. The road distance is 108.8 miles.
The best way to get from Sanford to Gainesville without a car is to train and bus via Orlando which takes 4h 16m and costs $20 - $35.
It takes approximately 4h 16m to get from Sanford to Gainesville, including transfers.
Yes, the driving distance between Sanford to Gainesville is 109 miles. It takes approximately 2h 19m to drive from Sanford to Gainesville.
There are 254+ hotels available in Gainesville.
What companies run services between Sanford, FL, USA and Gainesville, FL, USA?
There is no direct connection from Sanford to Gainesville. However, you can take the train to LYNX Central, walk to N Garland Ave & W Amelia St, take the line 25 bus to N John Young Pkwy & Business Center Blvd, walk to Orlando Bus Station, then take the bus to Gainesville. Alternatively, you can drive from Sanford to Gainesville in around 2h 19m.
- Phone
- +1 855-724-5411
- [email protected]
- Website
- SunRail
Train from Sanford to LYNX Central
- Ave. Duration
- 42 min
- Frequency
- Hourly
- Estimated price
- $2–4
- Website
- SunRail
Train from Sanford to Sand Lake Road
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SunRail
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orlando Bus Station to Gainesville
- Ave. Duration
- 1h 55m
- Frequency
- 4 times a day
- Estimated price
- $16–28
- Schedules at
- Flixbus USA
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Dr
- Ave. Duration
- 2h 20m
- Frequency
- 4 times a day
- Estimated price
- $29–60
- Website
- RedCoach
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