There are 8 ways to get from Sanford to Key Largo by train, bus, car, plane, shuttle, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus via Meadow Woods
best- Take the train from Sanford to Sand Lake Roadtrain
- Take the train from Orlando to Miamitrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
8h 31m$74–218Bus
cheapest- Take the bus from Orlando to Miami Airport Stationbus FlixBus 2411 / ...
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus Greyhound US0720s
9h 17m$48–83Train, bus
- Take the train from Sanford to Sand Lake Roadtrain
- Take the bus from Orlando - RedCoach Station, FL to Miami Airportbus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
9h 5m$68–133Drive 291.8 mi
- Drive from Sanford to Key Largocar 291.8 mi
5h 55m$54–77Train to Orlando, fly to Miami International Airport, shuttle
- Take the train from Sanford to Sand Lake Roadtrain
- Fly from Orlando (MCO) to Miami International Airport (MIA)plane MCO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
5h 50m$655–1,236Train, bus via Homestead
- Take the train from Winter Park Amtrak Station to Miami Amtrak Stationtrain Silver Meteor / ...
- Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus 301
11h 35m$97–192Train to Orlando, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the train from Sanford to Sand Lake Roadtrain
- Fly from Orlando (MCO) to Fort Lauderdale–Hollywood International Airport (FLL)plane MCO - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
6h 17m$375–756Fly Orlando Sanford to Key West International Airport, bus
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
- Take the bus from Key West Airport to Key Largo Bus Stopbus
5h 10m$53–275
Sanford to Key Largo by train, bus, and tram
Questions & Answers
The cheapest way to get from Sanford to Key Largo is to bus which costs $45 - $85 and takes 9h 17m.
The fastest way to get from Sanford to Key Largo is to fly and bus which takes 5h 10m and costs $50 - $280.
No, there is no direct bus from Sanford to Key Largo. However, there are services departing from N Garland Ave & W Amelia St and arriving at Key Largo Bus Stop via Orlando and Miami Airport Station. The journey, including transfers, takes approximately 9h 17m.
The distance between Sanford and Key Largo is 334 miles. The road distance is 293.5 miles.
The best way to get from Sanford to Key Largo without a car is to train and bus via Meadow Woods which takes 8h 31m and costs $70 - $220.
It takes approximately 8h 31m to get from Sanford to Key Largo, including transfers.
Sanford to Key Largo bus services, operated by Flixbus USA, depart from Orlando station.
Sanford to Key Largo bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Sanford to Key Largo is 294 miles. It takes approximately 5h 55m to drive from Sanford to Key Largo.
There are 315+ hotels available in Key Largo.
What companies run services between Sanford, FL, USA and Key Largo, FL, USA?
You can take a train from Sanford to Key Largo Bus Stop via LYNX Central, N Garland Ave & W Amelia St, Florida Mall, Orlando, and Miami Airport Station in around 9h 17m.
- Website
- southwest.com
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $35–260
Flights from Orlando to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $35–260
- Website
- aa.com
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $35–260
- Website
- jetblue.com
Flights from Orlando to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 9m
- When
- Every day
- Estimated price
- $35–260
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 20m
- When
- Thursday and Sunday
- Estimated price
- $35–250
- Phone
- +1 855-724-5411
- [email protected]
- Website
- sunrail.com
Train from Sanford to Sand Lake Road
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- https://sunrail.com
Train from Sanford to Sand Lake Road
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- https://sunrail.com
Train from Sanford to Sand Lake Road
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- https://sunrail.com
Train from Sanford to Sand Lake Road
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- https://sunrail.com
- Phone
- +1 831-539-2901
- [email protected]
- Website
- gobrightline.com
Train from Orlando to Miami
- Ave. Duration
- 3h 34m
- Frequency
- Every 2 hours
- Estimated price
- $40–170
- Book at
- https://www.gobrightline.com
- Smart
- $40–90
- Premium
- $110–170
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Winter Park Amtrak Station to Miami Amtrak Station
- Ave. Duration
- 6h 18m
- Frequency
- Twice daily
- Estimated price
- $85–180
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $8–17
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $8–17
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $8–17
- Website
- https://www.greyhound.com/
Bus from Key West Airport to Key Largo Bus Stop
- Ave. Duration
- 2h 50m
- Frequency
- 3 times a day
- Estimated price
- $14–28
- Website
- https://www.greyhound.com/
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Orlando - RedCoach Station, FL to Miami Airport
- Ave. Duration
- 4h 25m
- Frequency
- 4 times a day
- Estimated price
- $55–110
- Website
- https://www.redcoachusa.com
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- https://www.keysshuttle.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Orlando to Miami Airport Station
- Ave. Duration
- 4h 20m
- Frequency
- 5 times a day
- Estimated price
- $35–60
- Schedules at
- flixbus.com
- Phone
- 305-891-3131
- Website
- miamidade.gov
Bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largo
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- https://www.miamidade.gov/global/transportation/home.page
- Schedules at
- https://www.miamidade.gov/global/news-item.page?Mduid_news=news1778098763075690
- Adult
- $3
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