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How to get fromSanford to Key West (Island)by plane, train, bus, shuttle, car, or bus (Flixbus, Greyhound)

Find Transport to Key West (Island)

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There are 7 ways to get from Sanford to Key West (Island) by plane, train, bus, shuttle, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Orlando Sanford

    best
    1. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    1h 20m
    $35–250

  2. Train, bus, shuttle

    1. Take the train from Sanford to Sand Lake Roadtrain train
    2. Take the bus from Orlando - RedCoach Station, FL to Miami Airportbus bus
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    11h 39m
    $230–326

  3. Train, bus

    1. Take the train from Sanford to Sand Lake Roadtrain train
    2. Take the train from Orlando to Miamitrain train
    3. Take the bus from Miami Airport Station to Key West Airportbus bus
    11h 41m
    $89–246

  4. Drive 389 mi

    1. Drive from Sanford to Key Westcar car 389 mi
    8h 11m
    $71–103

  5. Train to Orlando, fly

    1. Take the train from Sanford to Sand Lake Roadtrain train
    2. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    3h 40m
    $75–656

  6. Bus

    1. Take the bus from Orlando to Miami Airport Stationbus bus FlixBus 2411 / ...
    2. Take the bus from Miami Airport Station to Key West Airportbus bus Greyhound US0720s
    12h 27m
    $58–111

  7. Train, bus via Pembroke Pines

    1. Take the train from Winter Park Amtrak Station to Hollywood Amtrak Stationtrain train Silver Meteor / ...
    2. Take the bus from Miami Airport Station to Key West Airportbus bus Greyhound US0720s
    13h 47m
    $104–224

Sanford to Key West (Island) by train, bus, and shuttle

Calendar21Weekly Services
Duration11h 39mAverage Duration
Ticket$230Cheapest Price
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Questions & Answers

Map of how to get from Sanford to Key West (Island).ExpandLaunch map view
  • Distance: 293.4 mi
  • Duration: 1h 20m

What companies run services between Sanford, FL, USA and Key West (Island), FL, USA?

Allegiant Air flies from Orlando Sanford (SFB) to Key West International Airport (EYW) twice a week. Alternatively, you can take a train from Sanford to Key West Airport via LYNX Central, N Garland Ave & W Amelia St, Florida Mall, Orlando, and Miami Airport Station in around 12h 27m.

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